A whole‐body circulatory neutrophil model with application to predicting clinical neutropenia from in vitro studies

A circulatory model of granulopoiesis and its regulation is presented that includes neutrophil trafficking in the lungs, liver, spleen, bone marrow, lymph nodes, and blood. In each organ, neutrophils undergo transendothelial migration from vascular to interstitial space, clearance due to apoptosis,...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Wenbo, Boras, Britton, Sung, Tae, Hu, Wenyue, Spilker, Mary E., D’Argenio, David Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302245/
https://www.ncbi.nlm.nih.gov/pubmed/33793091
http://dx.doi.org/10.1002/psp4.12620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302245/
https://www.ncbi.nlm.nih.gov/pubmed/33793091
http://dx.doi.org/10.1002/psp4.12620

Ejemplares similares