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Risk of SARS-CoV-2 virus transmission from donor corneal tissue: A review

Since the outbreak of respiratory coronavirus disease (COVID-19) caused by the coronavirus SARS-CoV-2, there is an ongoing discussion about whether the virus could be transmitted through corneal transplantation from donor to recipient. The purpose of this review was to summarize the current knowledg...

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Autores principales: Salz, Anna K, Acharya, Manisha, Hofmann, Nicola, Wittmershaus, Ilka, Sangwan, Virender, Börgel, Martin, Mathur, Umang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302275/
https://www.ncbi.nlm.nih.gov/pubmed/34011748
http://dx.doi.org/10.4103/ijo.IJO_3249_20
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author Salz, Anna K
Acharya, Manisha
Hofmann, Nicola
Wittmershaus, Ilka
Sangwan, Virender
Börgel, Martin
Mathur, Umang
author_facet Salz, Anna K
Acharya, Manisha
Hofmann, Nicola
Wittmershaus, Ilka
Sangwan, Virender
Börgel, Martin
Mathur, Umang
author_sort Salz, Anna K
collection PubMed
description Since the outbreak of respiratory coronavirus disease (COVID-19) caused by the coronavirus SARS-CoV-2, there is an ongoing discussion about whether the virus could be transmitted through corneal transplantation from donor to recipient. The purpose of this review was to summarize the current knowledge in the scientific community to provide aid in risk evaluation for potential virus transfer by corneal transplants. Literature was searched in PubMed.gov for relevant articles on coronavirus in conjunction with cornea processing, cornea transplantation and eye banking. Further, guidelines of health authorities and eye banking associations were reviewed. Studies have shown that SARS-CoV-2 RNA can be detected in ocular swabs and/or fluid of patients with COVID-19. However, the risk of SARS-CoV-2 virus transmission through these ocular tissues or fluid of patients is judged differently. To date, per literature and official guidelines, no evidence of viable virus in ocular tissue and no cases of transmission of SARS-CoV-2 via tissue preparations have been reported.
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spelling pubmed-83022752021-08-02 Risk of SARS-CoV-2 virus transmission from donor corneal tissue: A review Salz, Anna K Acharya, Manisha Hofmann, Nicola Wittmershaus, Ilka Sangwan, Virender Börgel, Martin Mathur, Umang Indian J Ophthalmol Expedited Publication, Review Article Since the outbreak of respiratory coronavirus disease (COVID-19) caused by the coronavirus SARS-CoV-2, there is an ongoing discussion about whether the virus could be transmitted through corneal transplantation from donor to recipient. The purpose of this review was to summarize the current knowledge in the scientific community to provide aid in risk evaluation for potential virus transfer by corneal transplants. Literature was searched in PubMed.gov for relevant articles on coronavirus in conjunction with cornea processing, cornea transplantation and eye banking. Further, guidelines of health authorities and eye banking associations were reviewed. Studies have shown that SARS-CoV-2 RNA can be detected in ocular swabs and/or fluid of patients with COVID-19. However, the risk of SARS-CoV-2 virus transmission through these ocular tissues or fluid of patients is judged differently. To date, per literature and official guidelines, no evidence of viable virus in ocular tissue and no cases of transmission of SARS-CoV-2 via tissue preparations have been reported. Wolters Kluwer - Medknow 2021-06 2021-05-21 /pmc/articles/PMC8302275/ /pubmed/34011748 http://dx.doi.org/10.4103/ijo.IJO_3249_20 Text en Copyright: © 2021 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Expedited Publication, Review Article
Salz, Anna K
Acharya, Manisha
Hofmann, Nicola
Wittmershaus, Ilka
Sangwan, Virender
Börgel, Martin
Mathur, Umang
Risk of SARS-CoV-2 virus transmission from donor corneal tissue: A review
title Risk of SARS-CoV-2 virus transmission from donor corneal tissue: A review
title_full Risk of SARS-CoV-2 virus transmission from donor corneal tissue: A review
title_fullStr Risk of SARS-CoV-2 virus transmission from donor corneal tissue: A review
title_full_unstemmed Risk of SARS-CoV-2 virus transmission from donor corneal tissue: A review
title_short Risk of SARS-CoV-2 virus transmission from donor corneal tissue: A review
title_sort risk of sars-cov-2 virus transmission from donor corneal tissue: a review
topic Expedited Publication, Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302275/
https://www.ncbi.nlm.nih.gov/pubmed/34011748
http://dx.doi.org/10.4103/ijo.IJO_3249_20
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