The Ablation of Envelope Protein Glycosylation Enhances the Neurovirulence of ZIKV and Cell Apoptosis in Newborn Mice

Zika virus (ZIKV) has attracted the wide global attention due to its causal link to microcephaly. In this study, two amino acid (aa) mutation (E143K and R3394K) were identified at the fourth generation (named ZKC2P4) during the serial passage of ZIKV-Asian lineage ZKC2/2016 strain in the newborn mou...

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Detalles Bibliográficos
Autores principales: Guo, Yanqing, Bao, Linlin, Xu, Yanfeng, Li, Fengdi, Lv, Qi, Fan, Feiyue, Qin, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302398/
https://www.ncbi.nlm.nih.gov/pubmed/34327243
http://dx.doi.org/10.1155/2021/5317662

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