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Signal strength controls the rate of polarization within CTLs during killing

Cytotoxic T lymphocytes (CTLs) are key effector cells in the immune response against viruses and cancers, killing targets with high precision. Target cell recognition by CTL triggers rapid polarization of intracellular organelles toward the synapse formed with the target cell, delivering cytolytic g...

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Detalles Bibliográficos
Autores principales:	Frazer, Gordon L., Gawden-Bone, Christian M., Dieckmann, Nele M.G., Asano, Yukako, Griffiths, Gillian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302442/ https://www.ncbi.nlm.nih.gov/pubmed/34292303 http://dx.doi.org/10.1083/jcb.202104093

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