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The immunodominant antibody response to Zika virus NS1 protein is characterized by cross-reactivity to self

Besides antigen-specific responses to viral antigens, humoral immune response in virus infection can generate polyreactive and autoreactive antibodies. Dengue and Zika virus infections have been linked to antibody-mediated autoimmune disorders, including Guillain-Barré syndrome. A unique feature of...

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Detalles Bibliográficos
Autores principales: Cavazzoni, Cecilia B., Bozza, Vicente B.T., Lucas, Tostes C.V., Conde, Luciana, Maia, Bruno, Mesin, Luka, Schiepers, Ariën, Ersching, Jonatan, Neris, Romulo L.S., Conde, Jonas N., Coelho, Diego R., Lima, Tulio M., Alvim, Renata G.F., Castilho, Leda R., de Paula Neto, Heitor A., Mohana-Borges, Ronaldo, Assunção-Miranda, Iranaia, Nobrega, Alberto, Victora, Gabriel D., Vale, Andre M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302445/
https://www.ncbi.nlm.nih.gov/pubmed/34292314
http://dx.doi.org/10.1084/jem.20210580