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Microglia in Alzheimer's disease at single-cell level. Are there common patterns in humans and mice?
Alzheimer’s disease (AD) is characterized by extracellular aggregates of amyloid β peptides, intraneuronal tau aggregates, and neuronal death. This pathology triggers activation of microglia. Because variants of genes expressed in microglia correlate with AD risk, microglial response to pathology pl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302448/ https://www.ncbi.nlm.nih.gov/pubmed/34292312 http://dx.doi.org/10.1084/jem.20202717 |