Identification of pathological transcription in autosomal dominant polycystic kidney disease epithelia

Autosomal dominant polycystic kidney disease (ADPKD) affects more than 12 million people worldwide. Mutations in PKD1 and PKD2 cause cyst formation through unknown mechanisms. To unravel the pathogenic mechanisms in ADPKD, multiple studies have investigated transcriptional mis-regulation in cystic k...

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Detalles Bibliográficos
Autores principales: Friedrich, Sebastian, Müller, Hannah, Riesterer, Caroline, Schüller, Hannah, Friedrich, Katja, Wörner, Carlotta Leonie, Busch, Tilman, Viau, Amandine, Kuehn, E. Wolfgang, Köttgen, Michael, Hofherr, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302622/
https://www.ncbi.nlm.nih.gov/pubmed/34301992
http://dx.doi.org/10.1038/s41598-021-94442-8

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