Induction of cryptic pre-mRNA splice-switching by antisense oligonucleotides

Antisense oligomers (AOs) are increasingly being used to modulate RNA splicing in live cells, both for research and for the development of therapeutics. While the most common intended effect of these AOs is to induce skipping of whole exons, rare examples are emerging of AOs that induce skipping of...

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Detalles Bibliográficos
Autores principales: Ham, Kristin A., Keegan, Niall P., McIntosh, Craig S., Aung-Htut, May T., Zaw, Khine, Greer, Kane, Fletcher, Sue, Wilton, Steve D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302632/
https://www.ncbi.nlm.nih.gov/pubmed/34302060
http://dx.doi.org/10.1038/s41598-021-94639-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302632/
https://www.ncbi.nlm.nih.gov/pubmed/34302060
http://dx.doi.org/10.1038/s41598-021-94639-x

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