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Mechanistic insight into bacterial entrapment by septin cage reconstitution
Septins are cytoskeletal proteins that assemble into hetero-oligomeric complexes and sense micron-scale membrane curvature. During infection with Shigella flexneri, an invasive enteropathogen, septins restrict actin tail formation by entrapping bacteria in cage-like structures. Here, we reconstitute...
Autores principales: | Lobato-Márquez, Damián, Xu, Jingwei, Güler, Gizem Özbaykal, Ojiakor, Adaobi, Pilhofer, Martin, Mostowy, Serge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302635/ https://www.ncbi.nlm.nih.gov/pubmed/34301939 http://dx.doi.org/10.1038/s41467-021-24721-5 |
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