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Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes

Patients with bipolar disorder (BIP) have a high risk of cardiovascular disease (CVD), despite considerable individual variation. The mechanisms underlying comorbid CVD in BIP remain largely unknown. We investigated polygenic overlap between BIP and CVD phenotypes, including CVD risk factors and cor...

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Detalles Bibliográficos
Autores principales: Rødevand, Linn, Bahrami, Shahram, Frei, Oleksandr, Chu, Yunhan, Shadrin, Alexey, O’Connell, Kevin S., Smeland, Olav B., Elvsåshagen, Torbjørn, Hindley, Guy F. L., Djurovic, Srdjan, Dale, Anders M., Lagerberg, Trine V., Steen, Nils Eiel, Andreassen, Ole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302675/
https://www.ncbi.nlm.nih.gov/pubmed/34301917
http://dx.doi.org/10.1038/s41398-021-01527-z