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GRP78 determines glioblastoma sensitivity to UBA1 inhibition-induced UPR signaling and cell death
Glioblastoma multiforme (GBM) is an extremely aggressive brain tumor for which new therapeutic approaches are urgently required. Unfolded protein response (UPR) plays an important role in the progression of GBM and is a promising target for developing novel therapeutic interventions. We identified u...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302679/ https://www.ncbi.nlm.nih.gov/pubmed/34301924 http://dx.doi.org/10.1038/s41419-021-04023-w |