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Initiating polyketide biosynthesis by on-line methyl esterification

Aurantinins (ARTs) are antibacterial polyketides featuring a unique 6/7/8/5-fused tetracyclic ring system and a triene side chain with a carboxyl terminus. Here we identify the art gene cluster and dissect ART’s C-methyl incorporation patterns to study its biosynthesis. During this process, an appar...

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Detalles Bibliográficos
Autores principales:	Li, Pengwei, Chen, Meng, Tang, Wei, Guo, Zhengyan, Zhang, Yuwei, Wang, Min, Horsman, Geoff P., Zhong, Jin, Lu, Zhaoxin, Chen, Yihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302727/ https://www.ncbi.nlm.nih.gov/pubmed/34301953 http://dx.doi.org/10.1038/s41467-021-24846-7

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