SARS-CoV-2 and pancreas: a potential pathological interaction?

The widespread extrapulmonary complications of coronavirus disease 2019 (COVID-19) have gained momentum; the pancreas is another major target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we take a closer look into potential pathological interactions. We provide an overview...

Descripción completa

Detalles Bibliográficos
Autores principales: Geravandi, Shirin, Mahmoudi-aznaveh, Azam, Azizi, Zahra, Maedler, Kathrin, Ardestani, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Forum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302839/
https://www.ncbi.nlm.nih.gov/pubmed/34373155
http://dx.doi.org/10.1016/j.tem.2021.07.004
_version_ 1783726956306497536
author Geravandi, Shirin
Mahmoudi-aznaveh, Azam
Azizi, Zahra
Maedler, Kathrin
Ardestani, Amin
author_facet Geravandi, Shirin
Mahmoudi-aznaveh, Azam
Azizi, Zahra
Maedler, Kathrin
Ardestani, Amin
author_sort Geravandi, Shirin
collection PubMed
description The widespread extrapulmonary complications of coronavirus disease 2019 (COVID-19) have gained momentum; the pancreas is another major target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we take a closer look into potential pathological interactions. We provide an overview of the current knowledge and understanding of SARS-CoV-2 infection of the pancreas with a special focus on pancreatic islets and propose direct, indirect, and systemic mechanisms for pancreas injury as result of the COVID-19–diabetes fatal bidirectional relationship.
format Online
Article
Text
id pubmed-8302839
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-83028392021-07-26 SARS-CoV-2 and pancreas: a potential pathological interaction? Geravandi, Shirin Mahmoudi-aznaveh, Azam Azizi, Zahra Maedler, Kathrin Ardestani, Amin Trends Endocrinol Metab Forum The widespread extrapulmonary complications of coronavirus disease 2019 (COVID-19) have gained momentum; the pancreas is another major target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we take a closer look into potential pathological interactions. We provide an overview of the current knowledge and understanding of SARS-CoV-2 infection of the pancreas with a special focus on pancreatic islets and propose direct, indirect, and systemic mechanisms for pancreas injury as result of the COVID-19–diabetes fatal bidirectional relationship. Elsevier Ltd. 2021-11 2021-07-24 /pmc/articles/PMC8302839/ /pubmed/34373155 http://dx.doi.org/10.1016/j.tem.2021.07.004 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Forum
Geravandi, Shirin
Mahmoudi-aznaveh, Azam
Azizi, Zahra
Maedler, Kathrin
Ardestani, Amin
SARS-CoV-2 and pancreas: a potential pathological interaction?
title SARS-CoV-2 and pancreas: a potential pathological interaction?
title_full SARS-CoV-2 and pancreas: a potential pathological interaction?
title_fullStr SARS-CoV-2 and pancreas: a potential pathological interaction?
title_full_unstemmed SARS-CoV-2 and pancreas: a potential pathological interaction?
title_short SARS-CoV-2 and pancreas: a potential pathological interaction?
title_sort sars-cov-2 and pancreas: a potential pathological interaction?
topic Forum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302839/
https://www.ncbi.nlm.nih.gov/pubmed/34373155
http://dx.doi.org/10.1016/j.tem.2021.07.004
work_keys_str_mv AT geravandishirin sarscov2andpancreasapotentialpathologicalinteraction
AT mahmoudiaznavehazam sarscov2andpancreasapotentialpathologicalinteraction
AT azizizahra sarscov2andpancreasapotentialpathologicalinteraction
AT maedlerkathrin sarscov2andpancreasapotentialpathologicalinteraction
AT ardestaniamin sarscov2andpancreasapotentialpathologicalinteraction

Ejemplares similares