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Proteases and variants: context matters for SARS-CoV-2 entry assays

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), like other coronaviruses, relies on a flexible array of entry mechanisms, driven by the spike (S) protein. Entry is dependent on proteolytic priming, activation, and receptor binding; all of which can be variable, dependent on context. He...

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Detalles Bibliográficos
Autores principales: Stevens, Christian S, Oguntuyo, Kasopefoluwa Y, Lee, Benhur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302850/
https://www.ncbi.nlm.nih.gov/pubmed/34365113
http://dx.doi.org/10.1016/j.coviro.2021.07.004

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