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Endovascular exclusion of the entire aortic arch with branched stent-grafts after surgery for acute type A aortic dissection

BACKGROUND: The treatment of residual pathology of the aortic arch after surgical repair for type A acute dissection (AAD) represents a therapeutic challenge. Recently, new branched endovascular devices have expanded the possibility of aortic arch stent-grafting (ASG) with proximal landing in zone 0...

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Autores principales: D'Onofrio, Augusto, Cibin, Giorgia, Antonello, Michele, Battocchio, Piero, Piazza, Michele, Caraffa, Raphael, Dall'Antonia, Alberto, Grego, Franco, Gerosa, Gino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302916/
https://www.ncbi.nlm.nih.gov/pubmed/34317796
http://dx.doi.org/10.1016/j.xjtc.2020.04.009
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author D'Onofrio, Augusto
Cibin, Giorgia
Antonello, Michele
Battocchio, Piero
Piazza, Michele
Caraffa, Raphael
Dall'Antonia, Alberto
Grego, Franco
Gerosa, Gino
author_facet D'Onofrio, Augusto
Cibin, Giorgia
Antonello, Michele
Battocchio, Piero
Piazza, Michele
Caraffa, Raphael
Dall'Antonia, Alberto
Grego, Franco
Gerosa, Gino
author_sort D'Onofrio, Augusto
collection PubMed
description BACKGROUND: The treatment of residual pathology of the aortic arch after surgical repair for type A acute dissection (AAD) represents a therapeutic challenge. Recently, new branched endovascular devices have expanded the possibility of aortic arch stent-grafting (ASG) with proximal landing in zone 0. The aim of this retrospective, single-center study was to evaluate outcomes of patients with a history of surgical repair for AAD undergoing ASG with branched devices. METHODS: We analyzed patients undergoing ASG after treatment for type AAD with 2 different branched devices: Nexus (dual-module, single branch, off-the-shelf) and RelayBranch (single-module, dual branch, custom-made). Before ASG, surgical bypass of supra-aortic vessels was performed according to patient's anatomy and to the selected device. All patients underwent clinical and computed tomography scan evaluation before hospital discharge, at 6 months, and on a yearly basis thereafter. RESULTS: From March 2017 to April 2019, 4 consecutive patients underwent ASG after surgery for AAD at our institution. Mean time from surgery for AAD to ASG was 20 months. Mean age at the time of ASG was 72 years. Nexus and Relay were implanted in 2 patients each. All patients survived and were successfully discharged. Mean intensive care unit stay and hospital stay were 3 and 19 days, respectively. We did not observe any major adverse events. At a mean follow-up of 28 months, all patients are alive and computed tomography scans showed good anatomic results with no endoleaks. CONCLUSIONS: This preliminary experience shows that ASG after surgery for AAD is feasible and provides encouraging clinical and anatomic early results.
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spelling pubmed-83029162021-07-26 Endovascular exclusion of the entire aortic arch with branched stent-grafts after surgery for acute type A aortic dissection D'Onofrio, Augusto Cibin, Giorgia Antonello, Michele Battocchio, Piero Piazza, Michele Caraffa, Raphael Dall'Antonia, Alberto Grego, Franco Gerosa, Gino JTCVS Tech Adult: Aorta BACKGROUND: The treatment of residual pathology of the aortic arch after surgical repair for type A acute dissection (AAD) represents a therapeutic challenge. Recently, new branched endovascular devices have expanded the possibility of aortic arch stent-grafting (ASG) with proximal landing in zone 0. The aim of this retrospective, single-center study was to evaluate outcomes of patients with a history of surgical repair for AAD undergoing ASG with branched devices. METHODS: We analyzed patients undergoing ASG after treatment for type AAD with 2 different branched devices: Nexus (dual-module, single branch, off-the-shelf) and RelayBranch (single-module, dual branch, custom-made). Before ASG, surgical bypass of supra-aortic vessels was performed according to patient's anatomy and to the selected device. All patients underwent clinical and computed tomography scan evaluation before hospital discharge, at 6 months, and on a yearly basis thereafter. RESULTS: From March 2017 to April 2019, 4 consecutive patients underwent ASG after surgery for AAD at our institution. Mean time from surgery for AAD to ASG was 20 months. Mean age at the time of ASG was 72 years. Nexus and Relay were implanted in 2 patients each. All patients survived and were successfully discharged. Mean intensive care unit stay and hospital stay were 3 and 19 days, respectively. We did not observe any major adverse events. At a mean follow-up of 28 months, all patients are alive and computed tomography scans showed good anatomic results with no endoleaks. CONCLUSIONS: This preliminary experience shows that ASG after surgery for AAD is feasible and provides encouraging clinical and anatomic early results. Elsevier 2020-04-28 /pmc/articles/PMC8302916/ /pubmed/34317796 http://dx.doi.org/10.1016/j.xjtc.2020.04.009 Text en © 2020 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Adult: Aorta
D'Onofrio, Augusto
Cibin, Giorgia
Antonello, Michele
Battocchio, Piero
Piazza, Michele
Caraffa, Raphael
Dall'Antonia, Alberto
Grego, Franco
Gerosa, Gino
Endovascular exclusion of the entire aortic arch with branched stent-grafts after surgery for acute type A aortic dissection
title Endovascular exclusion of the entire aortic arch with branched stent-grafts after surgery for acute type A aortic dissection
title_full Endovascular exclusion of the entire aortic arch with branched stent-grafts after surgery for acute type A aortic dissection
title_fullStr Endovascular exclusion of the entire aortic arch with branched stent-grafts after surgery for acute type A aortic dissection
title_full_unstemmed Endovascular exclusion of the entire aortic arch with branched stent-grafts after surgery for acute type A aortic dissection
title_short Endovascular exclusion of the entire aortic arch with branched stent-grafts after surgery for acute type A aortic dissection
title_sort endovascular exclusion of the entire aortic arch with branched stent-grafts after surgery for acute type a aortic dissection
topic Adult: Aorta
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302916/
https://www.ncbi.nlm.nih.gov/pubmed/34317796
http://dx.doi.org/10.1016/j.xjtc.2020.04.009
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