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Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis
Ensuring multiple sclerosis (MS) patients’ adherence to therapy is often challenging, but it is crucial to their survival and health-related quality of life (HRQoL). The aim of the present study was to outline connections between adherence, physical and mental HRQoL, levels of psychological readines...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303119/ https://www.ncbi.nlm.nih.gov/pubmed/34357139 http://dx.doi.org/10.3390/jpm11070672 |
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author | Buja, Alessandra Graffigna, Guendalina Mafrici, Simona F. Baldovin, Tatjana Pinato, Carlo Bolzonella, Umberto Barello, Serena Tognetto, Alessia Damiani, Gianfranco |
author_facet | Buja, Alessandra Graffigna, Guendalina Mafrici, Simona F. Baldovin, Tatjana Pinato, Carlo Bolzonella, Umberto Barello, Serena Tognetto, Alessia Damiani, Gianfranco |
author_sort | Buja, Alessandra |
collection | PubMed |
description | Ensuring multiple sclerosis (MS) patients’ adherence to therapy is often challenging, but it is crucial to their survival and health-related quality of life (HRQoL). The aim of the present study was to outline connections between adherence, physical and mental HRQoL, levels of psychological readiness to engage in a treatment, levels of social support, anthropometric, socio-demographic and clinical factors in patients suffering from MS. This cross-sectional study involved a sample of 237 Italian MS patients. A survey was conducted with a structured self-administered online questionnaire using validated measures of quality of life, adherence to therapy and anthropometric, socio-demographic, psychological and clinical variables. A path analysis was used to test the overall structure of the associations between the variables. The pathway indicates a positive association between mental health index and a stronger degree of engagement and being or having been in a long-term relationship. Physical health index was positively associated with age, having an occupation, and having a specific form of MS. Having had relapses in the previous year raised the odds of better adherence to therapy, while an increase in Body Mass Index (BMI) reduced them. Our findings could help in the management of MS patients, promoting behavioral interventions that take the psychological and socio-demographic peculiarities of each patient into account with a view to improving their adherence to therapy. |
format | Online Article Text |
id | pubmed-8303119 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83031192021-07-25 Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis Buja, Alessandra Graffigna, Guendalina Mafrici, Simona F. Baldovin, Tatjana Pinato, Carlo Bolzonella, Umberto Barello, Serena Tognetto, Alessia Damiani, Gianfranco J Pers Med Article Ensuring multiple sclerosis (MS) patients’ adherence to therapy is often challenging, but it is crucial to their survival and health-related quality of life (HRQoL). The aim of the present study was to outline connections between adherence, physical and mental HRQoL, levels of psychological readiness to engage in a treatment, levels of social support, anthropometric, socio-demographic and clinical factors in patients suffering from MS. This cross-sectional study involved a sample of 237 Italian MS patients. A survey was conducted with a structured self-administered online questionnaire using validated measures of quality of life, adherence to therapy and anthropometric, socio-demographic, psychological and clinical variables. A path analysis was used to test the overall structure of the associations between the variables. The pathway indicates a positive association between mental health index and a stronger degree of engagement and being or having been in a long-term relationship. Physical health index was positively associated with age, having an occupation, and having a specific form of MS. Having had relapses in the previous year raised the odds of better adherence to therapy, while an increase in Body Mass Index (BMI) reduced them. Our findings could help in the management of MS patients, promoting behavioral interventions that take the psychological and socio-demographic peculiarities of each patient into account with a view to improving their adherence to therapy. MDPI 2021-07-16 /pmc/articles/PMC8303119/ /pubmed/34357139 http://dx.doi.org/10.3390/jpm11070672 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Buja, Alessandra Graffigna, Guendalina Mafrici, Simona F. Baldovin, Tatjana Pinato, Carlo Bolzonella, Umberto Barello, Serena Tognetto, Alessia Damiani, Gianfranco Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis |
title | Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis |
title_full | Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis |
title_fullStr | Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis |
title_full_unstemmed | Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis |
title_short | Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis |
title_sort | adherence to therapy, physical and mental quality of life in patients with multiple sclerosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303119/ https://www.ncbi.nlm.nih.gov/pubmed/34357139 http://dx.doi.org/10.3390/jpm11070672 |
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