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Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis

Ensuring multiple sclerosis (MS) patients’ adherence to therapy is often challenging, but it is crucial to their survival and health-related quality of life (HRQoL). The aim of the present study was to outline connections between adherence, physical and mental HRQoL, levels of psychological readines...

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Autores principales: Buja, Alessandra, Graffigna, Guendalina, Mafrici, Simona F., Baldovin, Tatjana, Pinato, Carlo, Bolzonella, Umberto, Barello, Serena, Tognetto, Alessia, Damiani, Gianfranco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303119/
https://www.ncbi.nlm.nih.gov/pubmed/34357139
http://dx.doi.org/10.3390/jpm11070672
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author Buja, Alessandra
Graffigna, Guendalina
Mafrici, Simona F.
Baldovin, Tatjana
Pinato, Carlo
Bolzonella, Umberto
Barello, Serena
Tognetto, Alessia
Damiani, Gianfranco
author_facet Buja, Alessandra
Graffigna, Guendalina
Mafrici, Simona F.
Baldovin, Tatjana
Pinato, Carlo
Bolzonella, Umberto
Barello, Serena
Tognetto, Alessia
Damiani, Gianfranco
author_sort Buja, Alessandra
collection PubMed
description Ensuring multiple sclerosis (MS) patients’ adherence to therapy is often challenging, but it is crucial to their survival and health-related quality of life (HRQoL). The aim of the present study was to outline connections between adherence, physical and mental HRQoL, levels of psychological readiness to engage in a treatment, levels of social support, anthropometric, socio-demographic and clinical factors in patients suffering from MS. This cross-sectional study involved a sample of 237 Italian MS patients. A survey was conducted with a structured self-administered online questionnaire using validated measures of quality of life, adherence to therapy and anthropometric, socio-demographic, psychological and clinical variables. A path analysis was used to test the overall structure of the associations between the variables. The pathway indicates a positive association between mental health index and a stronger degree of engagement and being or having been in a long-term relationship. Physical health index was positively associated with age, having an occupation, and having a specific form of MS. Having had relapses in the previous year raised the odds of better adherence to therapy, while an increase in Body Mass Index (BMI) reduced them. Our findings could help in the management of MS patients, promoting behavioral interventions that take the psychological and socio-demographic peculiarities of each patient into account with a view to improving their adherence to therapy.
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spelling pubmed-83031192021-07-25 Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis Buja, Alessandra Graffigna, Guendalina Mafrici, Simona F. Baldovin, Tatjana Pinato, Carlo Bolzonella, Umberto Barello, Serena Tognetto, Alessia Damiani, Gianfranco J Pers Med Article Ensuring multiple sclerosis (MS) patients’ adherence to therapy is often challenging, but it is crucial to their survival and health-related quality of life (HRQoL). The aim of the present study was to outline connections between adherence, physical and mental HRQoL, levels of psychological readiness to engage in a treatment, levels of social support, anthropometric, socio-demographic and clinical factors in patients suffering from MS. This cross-sectional study involved a sample of 237 Italian MS patients. A survey was conducted with a structured self-administered online questionnaire using validated measures of quality of life, adherence to therapy and anthropometric, socio-demographic, psychological and clinical variables. A path analysis was used to test the overall structure of the associations between the variables. The pathway indicates a positive association between mental health index and a stronger degree of engagement and being or having been in a long-term relationship. Physical health index was positively associated with age, having an occupation, and having a specific form of MS. Having had relapses in the previous year raised the odds of better adherence to therapy, while an increase in Body Mass Index (BMI) reduced them. Our findings could help in the management of MS patients, promoting behavioral interventions that take the psychological and socio-demographic peculiarities of each patient into account with a view to improving their adherence to therapy. MDPI 2021-07-16 /pmc/articles/PMC8303119/ /pubmed/34357139 http://dx.doi.org/10.3390/jpm11070672 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Buja, Alessandra
Graffigna, Guendalina
Mafrici, Simona F.
Baldovin, Tatjana
Pinato, Carlo
Bolzonella, Umberto
Barello, Serena
Tognetto, Alessia
Damiani, Gianfranco
Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis
title Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis
title_full Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis
title_fullStr Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis
title_full_unstemmed Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis
title_short Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis
title_sort adherence to therapy, physical and mental quality of life in patients with multiple sclerosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303119/
https://www.ncbi.nlm.nih.gov/pubmed/34357139
http://dx.doi.org/10.3390/jpm11070672
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