Development of Randomized Trials in Adults with Medulloblastoma—The Example of EORTC 1634-BTG/NOA-23

SIMPLE SUMMARY: Medulloblastoma is rare after puberty. Among several molecular subgroups that have been described, the sonic hedgehog (SHH) subgroup is highly overrepresented in the post-pubertal population and can be targeted with smoothened (SMO) inhibitors. However, no practice-changing prospecti...

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Detalles Bibliográficos
Autores principales: Hau, Peter, Frappaz, Didier, Hovey, Elizabeth, McCabe, Martin G., Pajtler, Kristian W., Wiestler, Benedikt, Seidel, Clemens, Combs, Stephanie E., Dirven, Linda, Klein, Martin, Anazodo, Antoinette, Hattingen, Elke, Hofer, Silvia, Pfister, Stefan M., Zimmer, Claus, Kortmann, Rolf-Dieter, Sunyach, Marie-Pierre, Tanguy, Ronan, Effeney, Rachel, von Deimling, Andreas, Sahm, Felix, Rutkowski, Stefan, Berghoff, Anna S., Franceschi, Enrico, Pineda, Estela, Beier, Dagmar, Peeters, Ellen, Gorlia, Thierry, Vanlancker, Maureen, Bromberg, Jacoline E. C., Gautier, Julien, Ziegler, David S., Preusser, Matthias, Wick, Wolfgang, Weller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303185/
https://www.ncbi.nlm.nih.gov/pubmed/34298664
http://dx.doi.org/10.3390/cancers13143451

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