Marine Antitumor Peptide Dolastatin 10: Biological Activity, Structural Modification and Synthetic Chemistry

Dolastatin 10 (Dol-10), a leading marine pentapeptide isolated from the Indian Ocean mollusk Dolabella auricularia, contains three unique amino acid residues. Dol-10 can effectively induce apoptosis of lung cancer cells and other tumor cells at nanomolar concentration, and it has been developed into...

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Detalles Bibliográficos
Autores principales: Gao, Gang, Wang, Yanbing, Hua, Huiming, Li, Dahong, Tang, Chunlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303260/
https://www.ncbi.nlm.nih.gov/pubmed/34202685
http://dx.doi.org/10.3390/md19070363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303260/
https://www.ncbi.nlm.nih.gov/pubmed/34202685
http://dx.doi.org/10.3390/md19070363

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