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Induced Pluripotent Stem Cell-Derived Neural Precursors Improve Memory, Synaptic and Pathological Abnormalities in a Mouse Model of Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common type of dementia in the elderly population. The disease is characterized by progressive memory loss, cerebral atrophy, extensive neuronal loss, synaptic alterations, brain inflammation, extracellular accumulation of amyloid-β (Aβ) plaques, and intracellula...
Autores principales: | Armijo, Enrique, Edwards, George, Flores, Andrea, Vera, Jorge, Shahnawaz, Mohammad, Moda, Fabio, Gonzalez, Cesar, Sanhueza, Magdalena, Soto, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303262/ https://www.ncbi.nlm.nih.gov/pubmed/34359972 http://dx.doi.org/10.3390/cells10071802 |
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