Effects of (R)- and (S)-α-Hydroxylation of Acyl Chains in Sphingosine, Dihydrosphingosine, and Phytosphingosine Ceramides on Phase Behavior and Permeability of Skin Lipid Models

Ceramides (Cers) with α-hydroxylated acyl chains comprise about a third of all extractable skin Cers and are required for permeability barrier homeostasis. We have probed here the effects of Cer hydroxylation on their behavior in lipid models comprising the major SC lipids, Cer/free fatty acids (C (...

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Detalles Bibliográficos
Autores principales: Kováčik, Andrej, Pullmannová, Petra, Opálka, Lukáš, Šilarová, Michaela, Maixner, Jaroslav, Vávrová, Kateřina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303283/
https://www.ncbi.nlm.nih.gov/pubmed/34299088
http://dx.doi.org/10.3390/ijms22147468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303283/
https://www.ncbi.nlm.nih.gov/pubmed/34299088
http://dx.doi.org/10.3390/ijms22147468

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