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Clinical Outcome of Rotational Atherectomy in Calcified Lesions in Korea-ROCK Registry

Background and Objectives: Data is still limited regarding clinical outcomes of rotational atherectomy (RA) after percutaneous coronary intervention. We sought to evaluate clinical outcomes of RA. Materials and Methods: This multi-center registry enrolled patients who underwent RA during PCI from ni...

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Autores principales: Lee, Kyusup, Jung, Ji-hoon, Lee, Myunhee, Kim, Dae-Won, Park, Mahn-Won, Choi, Ik-Jun, Lee, Jae-Hwan, Lee, Jang-Hoon, Lee, Sang-Rok, Lee, Pil-Hyung, Lee, Seung-Whan, Yoo, Ki-Dong, Yun, Kyeong-Ho, Lee, Hyun-Jong, Her, Sung-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303478/
https://www.ncbi.nlm.nih.gov/pubmed/34356975
http://dx.doi.org/10.3390/medicina57070694
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author Lee, Kyusup
Jung, Ji-hoon
Lee, Myunhee
Kim, Dae-Won
Park, Mahn-Won
Choi, Ik-Jun
Lee, Jae-Hwan
Lee, Jang-Hoon
Lee, Sang-Rok
Lee, Pil-Hyung
Lee, Seung-Whan
Yoo, Ki-Dong
Yun, Kyeong-Ho
Lee, Hyun-Jong
Her, Sung-Ho
author_facet Lee, Kyusup
Jung, Ji-hoon
Lee, Myunhee
Kim, Dae-Won
Park, Mahn-Won
Choi, Ik-Jun
Lee, Jae-Hwan
Lee, Jang-Hoon
Lee, Sang-Rok
Lee, Pil-Hyung
Lee, Seung-Whan
Yoo, Ki-Dong
Yun, Kyeong-Ho
Lee, Hyun-Jong
Her, Sung-Ho
author_sort Lee, Kyusup
collection PubMed
description Background and Objectives: Data is still limited regarding clinical outcomes of rotational atherectomy (RA) after percutaneous coronary intervention. We sought to evaluate clinical outcomes of RA. Materials and Methods: This multi-center registry enrolled patients who underwent RA during PCI from nine tertiary centers in Korea between January 2010 and October 2019. The primary endpoint was target-vessel failure (TVF; the composite outcome of cardiac death, target-vessel spontaneous myocardial infarction, or target-vessel revascularization). Results: Of 540 patients (583 lesions), the mean patient age was 71.4 ± 0.4 years, 323 patients (59.8%) were men, and 305 patients (56.5%) had diabetes mellitus. Technical success rate was 96.4%. In-hospital major adverse cerebral and cardiac events occurred in 63 cases (10.8%). At 1.5 years, 72 (16.0%) of TVFs were occurred. We evaluated independent predictors of TVF, which included current smoker (hazard ratio (HR), 1.92; 95% confidence interval (CI), 1.17–3.16; p = 0.01), chronic renal disease (HR, 1.87; 95% CI, 1.14–3.08; p = 0.013), history of cerebrovascular attack (HR, 2.14; 95% CI, 1.24-3.68; p = 0.006), left ventricle ejection fraction (HR, 0.98; 95% CI, 0.97–0.999; p = 0.037), and left main disease (HR, 1.94; 95% CI, 1.11–3.37; p = 0.019). Conclusions: From this registry, we demonstrated acceptable success rates, in-hospital and mid-term clinical outcomes of RA in the DES era.
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spelling pubmed-83034782021-07-25 Clinical Outcome of Rotational Atherectomy in Calcified Lesions in Korea-ROCK Registry Lee, Kyusup Jung, Ji-hoon Lee, Myunhee Kim, Dae-Won Park, Mahn-Won Choi, Ik-Jun Lee, Jae-Hwan Lee, Jang-Hoon Lee, Sang-Rok Lee, Pil-Hyung Lee, Seung-Whan Yoo, Ki-Dong Yun, Kyeong-Ho Lee, Hyun-Jong Her, Sung-Ho Medicina (Kaunas) Article Background and Objectives: Data is still limited regarding clinical outcomes of rotational atherectomy (RA) after percutaneous coronary intervention. We sought to evaluate clinical outcomes of RA. Materials and Methods: This multi-center registry enrolled patients who underwent RA during PCI from nine tertiary centers in Korea between January 2010 and October 2019. The primary endpoint was target-vessel failure (TVF; the composite outcome of cardiac death, target-vessel spontaneous myocardial infarction, or target-vessel revascularization). Results: Of 540 patients (583 lesions), the mean patient age was 71.4 ± 0.4 years, 323 patients (59.8%) were men, and 305 patients (56.5%) had diabetes mellitus. Technical success rate was 96.4%. In-hospital major adverse cerebral and cardiac events occurred in 63 cases (10.8%). At 1.5 years, 72 (16.0%) of TVFs were occurred. We evaluated independent predictors of TVF, which included current smoker (hazard ratio (HR), 1.92; 95% confidence interval (CI), 1.17–3.16; p = 0.01), chronic renal disease (HR, 1.87; 95% CI, 1.14–3.08; p = 0.013), history of cerebrovascular attack (HR, 2.14; 95% CI, 1.24-3.68; p = 0.006), left ventricle ejection fraction (HR, 0.98; 95% CI, 0.97–0.999; p = 0.037), and left main disease (HR, 1.94; 95% CI, 1.11–3.37; p = 0.019). Conclusions: From this registry, we demonstrated acceptable success rates, in-hospital and mid-term clinical outcomes of RA in the DES era. MDPI 2021-07-07 /pmc/articles/PMC8303478/ /pubmed/34356975 http://dx.doi.org/10.3390/medicina57070694 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Kyusup
Jung, Ji-hoon
Lee, Myunhee
Kim, Dae-Won
Park, Mahn-Won
Choi, Ik-Jun
Lee, Jae-Hwan
Lee, Jang-Hoon
Lee, Sang-Rok
Lee, Pil-Hyung
Lee, Seung-Whan
Yoo, Ki-Dong
Yun, Kyeong-Ho
Lee, Hyun-Jong
Her, Sung-Ho
Clinical Outcome of Rotational Atherectomy in Calcified Lesions in Korea-ROCK Registry
title Clinical Outcome of Rotational Atherectomy in Calcified Lesions in Korea-ROCK Registry
title_full Clinical Outcome of Rotational Atherectomy in Calcified Lesions in Korea-ROCK Registry
title_fullStr Clinical Outcome of Rotational Atherectomy in Calcified Lesions in Korea-ROCK Registry
title_full_unstemmed Clinical Outcome of Rotational Atherectomy in Calcified Lesions in Korea-ROCK Registry
title_short Clinical Outcome of Rotational Atherectomy in Calcified Lesions in Korea-ROCK Registry
title_sort clinical outcome of rotational atherectomy in calcified lesions in korea-rock registry
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303478/
https://www.ncbi.nlm.nih.gov/pubmed/34356975
http://dx.doi.org/10.3390/medicina57070694
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