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Stereotactic Body Radiotherapy for Patients with Lung Oligometastatic Disease: A Five-Year Systematic Review
SIMPLE SUMMARY: Stereotactic body radiation therapy (SBRT) is currently used to treat lung metastasis, particularly in the setting of oligometastatic disease. Objective of this treatment is lesion’s ablation. However, its techniques, efficacy, and safety remain to be evaluated. Several teams have pu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303507/ https://www.ncbi.nlm.nih.gov/pubmed/34298836 http://dx.doi.org/10.3390/cancers13143623 |
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author | Virbel, Guillaume Le Fèvre, Clara Noël, Georges Antoni, Delphine |
author_facet | Virbel, Guillaume Le Fèvre, Clara Noël, Georges Antoni, Delphine |
author_sort | Virbel, Guillaume |
collection | PubMed |
description | SIMPLE SUMMARY: Stereotactic body radiation therapy (SBRT) is currently used to treat lung metastasis, particularly in the setting of oligometastatic disease. Objective of this treatment is lesion’s ablation. However, its techniques, efficacy, and safety remain to be evaluated. Several teams have published their experiences with different radiotherapy schedules. The aim of this review was to analyze these topics in regard to the last five years of publications. For this purpose, we carried out a systematic review of the literature using the PRISMA method. This review can help oncologists involved in lung oligometastasis to clarify their knowledge through the wealth of published data and may lead to improved management. ABSTRACT: For several years, oligometastatic disease has represented an intermediate state between localized disease accessible to local treatment and multimetastatic disease requiring systemic therapy. The lung represents one of the most common metastatic locations. Stereotactic body radiation therapy (SBRT) appears to be the treatment of choice for these patients. There are few data defining the place of radiotherapy and reporting outcome after SBRT in lung metastases. This 5-year review aimed to determine areas of SBRT usefulness and methods for the management of pulmonary metastasis in oligometastatic patients. A search for articles on PubMed allowed selection of the most relevant studies. Eighteen articles were selected according to pre-established criteria for this purpose. The analysis concludes that SBRT is an effective and safe treatment in selected patients when the disease remains localized from one to three organs. |
format | Online Article Text |
id | pubmed-8303507 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83035072021-07-25 Stereotactic Body Radiotherapy for Patients with Lung Oligometastatic Disease: A Five-Year Systematic Review Virbel, Guillaume Le Fèvre, Clara Noël, Georges Antoni, Delphine Cancers (Basel) Systematic Review SIMPLE SUMMARY: Stereotactic body radiation therapy (SBRT) is currently used to treat lung metastasis, particularly in the setting of oligometastatic disease. Objective of this treatment is lesion’s ablation. However, its techniques, efficacy, and safety remain to be evaluated. Several teams have published their experiences with different radiotherapy schedules. The aim of this review was to analyze these topics in regard to the last five years of publications. For this purpose, we carried out a systematic review of the literature using the PRISMA method. This review can help oncologists involved in lung oligometastasis to clarify their knowledge through the wealth of published data and may lead to improved management. ABSTRACT: For several years, oligometastatic disease has represented an intermediate state between localized disease accessible to local treatment and multimetastatic disease requiring systemic therapy. The lung represents one of the most common metastatic locations. Stereotactic body radiation therapy (SBRT) appears to be the treatment of choice for these patients. There are few data defining the place of radiotherapy and reporting outcome after SBRT in lung metastases. This 5-year review aimed to determine areas of SBRT usefulness and methods for the management of pulmonary metastasis in oligometastatic patients. A search for articles on PubMed allowed selection of the most relevant studies. Eighteen articles were selected according to pre-established criteria for this purpose. The analysis concludes that SBRT is an effective and safe treatment in selected patients when the disease remains localized from one to three organs. MDPI 2021-07-20 /pmc/articles/PMC8303507/ /pubmed/34298836 http://dx.doi.org/10.3390/cancers13143623 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Systematic Review Virbel, Guillaume Le Fèvre, Clara Noël, Georges Antoni, Delphine Stereotactic Body Radiotherapy for Patients with Lung Oligometastatic Disease: A Five-Year Systematic Review |
title | Stereotactic Body Radiotherapy for Patients with Lung Oligometastatic Disease: A Five-Year Systematic Review |
title_full | Stereotactic Body Radiotherapy for Patients with Lung Oligometastatic Disease: A Five-Year Systematic Review |
title_fullStr | Stereotactic Body Radiotherapy for Patients with Lung Oligometastatic Disease: A Five-Year Systematic Review |
title_full_unstemmed | Stereotactic Body Radiotherapy for Patients with Lung Oligometastatic Disease: A Five-Year Systematic Review |
title_short | Stereotactic Body Radiotherapy for Patients with Lung Oligometastatic Disease: A Five-Year Systematic Review |
title_sort | stereotactic body radiotherapy for patients with lung oligometastatic disease: a five-year systematic review |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303507/ https://www.ncbi.nlm.nih.gov/pubmed/34298836 http://dx.doi.org/10.3390/cancers13143623 |
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