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Clinicopathological and Genomic Profiles of Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma Identify Overlapping Signatures with a High Mutational Burden

Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) are rare tumors developing in chronically sun-exposed skin. Clinicopathological features are similar, but they differ in prognosis, while PDS has a more aggressive course with a higher risk for local recurrence and metastases. In curr...

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Detalles Bibliográficos
Autores principales: Ak, Melike, Kahraman, Abdullah, Arnold, Fabian M., Turko, Patrick, Levesque, Mitchell P., Zoche, Martin, Ramelyte, Egle, Dummer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303615/
https://www.ncbi.nlm.nih.gov/pubmed/34202213
http://dx.doi.org/10.3390/genes12070974