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Trastuzumab Mechanism of Action; 20 Years of Research to Unravel a Dilemma

SIMPLE SUMMARY: Overexpression of HER2 receptors have been identified in various types of cancer including breast cancer and ovarian cancer. HER2 overexpression is generally associated with poor clinical outcomes in patients with HER2-positve tumors. Trastuzumab, an antibody specifically targeting H...

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Detalles Bibliográficos
Autores principales:	Maadi, Hamid, Soheilifar, Mohammad Hasan, Choi, Won-Shik, Moshtaghian, Abdolvahab, Wang, Zhixiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303665/ https://www.ncbi.nlm.nih.gov/pubmed/34298754 http://dx.doi.org/10.3390/cancers13143540

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