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Analysis of Genetic Variants Associated with Levels of Immune Modulating Proteins for Impact on Alzheimer’s Disease Risk Reveal a Potential Role for SIGLEC14
Genome-wide association studies (GWAS) have identified immune-related genes as risk factors for Alzheimer’s disease (AD), including TREM2 and CD33, frequently passing a stringent false-discovery rate. These genes either encode or signal through immunomodulatory tyrosine-phosphorylated inhibitory mot...
Autores principales: | Shaw, Benjamin C., Katsumata, Yuriko, Simpson, James F., Fardo, David W., Estus, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303736/ https://www.ncbi.nlm.nih.gov/pubmed/34208838 http://dx.doi.org/10.3390/genes12071008 |
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