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The Prostate Cancer Therapy Enzalutamide Compared with Abiraterone Acetate/Prednisone Impacts Motivation for Exploration, Spatial Learning and Alters Dopaminergic Transmission in Aged Castrated Mice

SIMPLE SUMMARY: Cognitive side effects and fatigue after cancer treatment now constitute a major challenge in oncology. Abiraterone acetate plus prednisone (AAP) and enzalutamide (ENZ) are next-generation therapies improving metastatic castration-resistant prostate cancer (mCRPC) patient survival, b...

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Detalles Bibliográficos
Autores principales: Nicola, Celeste, Dubois, Martine, Campart, Cynthia, Al Sagheer, Tareq, Desrues, Laurence, Schapman, Damien, Galas, Ludovic, Lange, Marie, Joly, Florence, Castel, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304001/
https://www.ncbi.nlm.nih.gov/pubmed/34298734
http://dx.doi.org/10.3390/cancers13143518