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Select Porcine Elongation Factor 1α Sequences Mediate Stable High-Level and Upregulated Expression of Heterologous Genes in Porcine Cells in Response to Primate Serum

Genetically engineered (GE) pigs with various combinations of genetic profiles have been developed using heterologous promoters. This study aimed to identify autologous promoters for high and ubiquitous expression of xenotransplantation relevant genes in GE pigs. A 1.4 kb upstream regulatory sequenc...

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Detalles Bibliográficos
Autores principales:	Sun, Wu-Sheng, Yang, Hyeon, No, Jin Gu, Lee, Haesun, Lee, Nahyun, Lee, Minguk, Kang, Man-Jong, Oh, Keon Bong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304002/ https://www.ncbi.nlm.nih.gov/pubmed/34356062 http://dx.doi.org/10.3390/genes12071046

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