Cargando…

Short Chain Fatty Acid Acetate Increases TNFα-Induced MCP-1 Production in Monocytic Cells via ACSL1/MAPK/NF-κB Axis

Short-chain fatty acid (SCFA) acetate, a byproduct of dietary fiber metabolism by gut bacteria, has multiple immunomodulatory functions. The anti-inflammatory role of acetate is well documented; however, its effect on monocyte chemoattractant protein-1 (MCP-1) production is unknown. Similarly, the c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al-Roub, Areej, Akhter, Nadeem, Al-Sayyar, Amnah, Wilson, Ajit, Thomas, Reeby, Kochumon, Shihab, Al-Rashed, Fatema, Al-Mulla, Fahd, Sindhu, Sardar, Ahmad, Rasheed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304091/ https://www.ncbi.nlm.nih.gov/pubmed/34299302 http://dx.doi.org/10.3390/ijms22147683

Ejemplares similares

ROS/TNF-α Crosstalk Triggers the Expression of IL-8 and MCP-1 in Human Monocytic THP-1 Cells via the NF-κB and ERK1/2 Mediated Signaling
por: Akhter, Nadeem, et al.
Publicado: (2021)

TNFα induces matrix metalloproteinase-9 expression in monocytic cells through ACSL1/JNK/ERK/NF-kB signaling pathways
por: Al-Roub, Areej, et al.
Publicado: (2023)

ACSL1 Regulates TNFα-Induced GM-CSF Production by Breast Cancer MDA-MB-231 Cells
por: Thomas, Reeby, et al.
Publicado: (2019)

Endoplasmic Reticulum Stress Promotes the Expression of TNF-α in THP-1 Cells by Mechanisms Involving ROS/CHOP/HIF-1α and MAPK/NF-κB Pathways
por: Akhter, Nadeem, et al.
Publicado: (2023)

Expression of Steroid Receptor RNA Activator 1 (SRA1) in the Adipose Tissue Is Associated with TLRs and IRFs in Diabesity
por: Kochumon, Shihab, et al.
Publicado: (2022)

TNF-α in Combination with Palmitate Enhances IL-8 Production via The MyD88- Independent TLR4 Signaling Pathway: Potential Relevance to Metabolic Inflammation
por: Hasan, Amal, et al.
Publicado: (2019)

Dectin-1 as a Potential Inflammatory Biomarker for Metabolic Inflammation in Adipose Tissue of Individuals with Obesity
por: Al Madhoun, Ashraf, et al.
Publicado: (2022)

TNF-α Increases IP-10 Expression in MCF-7 Breast Cancer Cells via Activation of the JNK/c-Jun Pathways
por: Kochumon, Shihab, et al.
Publicado: (2021)

Elevated adipose tissue associated IL-2 expression in obesity correlates with metabolic inflammation and insulin resistance
por: Kochumon, Shihab, et al.
Publicado: (2020)

ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding
por: Al-Rashed, Fatema, et al.
Publicado: (2023)

LPS Induces GM-CSF Production by Breast Cancer MDA-MB-231 Cells via Long-Chain Acyl-CoA Synthetase 1
por: Al-Rashed, Fatema, et al.
Publicado: (2020)

Enhanced Adipose Expression of Interferon Regulatory Factor (IRF)-5 Associates with the Signatures of Metabolic Inflammation in Diabetic Obese Patients
por: Sindhu, Sardar, et al.
Publicado: (2020)

Increased Adipose Tissue Expression of IL-23 Associates with Inflammatory Markers in People with High LDL Cholesterol
por: Kochumon, Shihab, et al.
Publicado: (2022)

IFN-γ and LPS Induce Synergistic Expression of CCL2 in Monocytic Cells via H3K27 Acetylation
por: Akhter, Nadeem, et al.
Publicado: (2022)

IL-1β and TNFα Cooperativity in Regulating IL-6 Expression in Adipocytes Depends on CREB Binding and H3K14 Acetylation
por: Al-Roub, Areej, et al.
Publicado: (2021)

Repetitive Intermittent Hyperglycemia Drives the M1 Polarization and Inflammatory Responses in THP-1 Macrophages Through the Mechanism Involving the TLR4-IRF5 Pathway
por: Al-Rashed, Fatema, et al.
Publicado: (2020)

Increased Adipose Tissue Expression of Interferon Regulatory Factor (IRF)-5 in Obesity: Association with Metabolic Inflammation
por: Sindhu, Sardar, et al.
Publicado: (2019)

The Cooperative Induction of CCL4 in Human Monocytic Cells by TNF-α and Palmitate Requires MyD88 and Involves MAPK/NF-κB Signaling Pathways
por: Sindhu, Sardar, et al.
Publicado: (2019)

Adipose Tissue Steroid Receptor RNA Activator 1 (SRA1) Expression Is Associated with Obesity, Insulin Resistance, and Inflammation
por: Kochumon, Shihab, et al.
Publicado: (2021)

Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cells
por: Al-Rashed, Fatema, et al.
Publicado: (2021)

MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress
por: Sindhu, Sardar, et al.
Publicado: (2020)

Adipose Tissue Caveolin-1 Upregulation in Obesity Involves TNF-α/NF-κB Mediated Signaling
por: Al Madhoun, Ashraf, et al.
Publicado: (2023)

Increased adipose tissue expression of IL‐18R and its ligand IL‐18 associates with inflammation and insulin resistance in obesity
por: Ahmad, Rasheed, et al.
Publicado: (2017)

Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway
por: Kochumon, Shihab, et al.
Publicado: (2020)

Adipose tissue gene expression of CXCL10 and CXCL11 modulates inflammatory markers in obesity: implications for metabolic inflammation and insulin resistance
por: Kochumon, Shihab, et al.
Publicado: (2020)

Increased adipose tissue expression of TLR8 in obese individuals with or without type-2 diabetes: significance in metabolic inflammation
por: Ahmad, Rasheed, et al.
Publicado: (2016)

TLR2 and AP-1/NF-kappaB are involved in the regulation of MMP-9 elicited by heat killed Listeria monocytogenes in human monocytic THP-1 cells
por: Shihab, Puthiyaveetil Kochumon, et al.
Publicado: (2015)

Short Sleep Duration and Its Association with Obesity and Other Metabolic Risk Factors in Kuwaiti Urban Adults
por: Al-Rashed, Fatema, et al.
Publicado: (2021)

Increased circulatory levels of fractalkine (CX3CL1) are associated with inflammatory chemokines and cytokines in individuals with type-2 diabetes
por: Sindhu, Sardar, et al.
Publicado: (2017)

Differential association of plasma monocyte chemoattractant protein-1 with systemic inflammatory and airway remodeling biomarkers in type-2 diabetic patients with and without asthma
por: Sindhu, Sardar, et al.
Publicado: (2016)

Erratum to: ‘Differential association of plasma monocyte chemoattractant protein-1 with systemic inflammatory and airway remodeling biomarkers in type-2 diabetic patients with and without asthma’
por: Sindhu, Sardar, et al.
Publicado: (2016)

Increasing the Duration of Light Physical Activity Ameliorates Insulin Resistance Syndrome in Metabolically Healthy Obese Adults
por: Al-Rashed, Fatema, et al.
Publicado: (2020)

Caveolin-1 rs1997623 Single Nucleotide Polymorphism Creates a New Binding Site for the Early B-Cell Factor 1 That Instigates Adipose Tissue CAV1 Protein Overexpression
por: Al Madhoun, Ashraf, et al.
Publicado: (2022)

Low carbohydrate intake correlates with trends of insulin resistance and metabolic acidosis in healthy lean individuals
por: Al-Reshed, Fatema, et al.
Publicado: (2023)

Increased expression of the interleukin-1 receptor-associated kinase (IRAK)-1 is associated with adipose tissue inflammatory state in obesity
por: Ahmad, Rasheed, et al.
Publicado: (2015)

TLR4/MyD88 -mediated CCL2 production by lipopolysaccharide (endotoxin): Implications for metabolic inflammation
por: Akhter, Nadeem, et al.
Publicado: (2018)

Correlation Profile of Suppression of Tumorigenicity 2 and/or Interleukin-33 with Biomarkers in the Adipose Tissue of Individuals with Different Metabolic States
por: Hasan, Amal, et al.
Publicado: (2020)

Cysteine dioxygenase type 1: A new player in adipose physiology and metabolic health
por: Sindhu, Sardar, et al.
Publicado: (2022)

Adipose tissue expression of CCL19 chemokine is positively associated with insulin resistance
por: Kochumon, Shihab, et al.
Publicado: (2018)

Microarray analysis reveals ONC201 mediated differential mechanisms of CHOP gene regulation in metastatic and nonmetastatic colorectal cancer cells
por: Al Madhoun, Ashraf, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_o05930dkas8ibghb2e12msq34k