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The Effect of Mipomersen in the Management of Patients with Familial Hypercholesterolemia: A Systematic Review and Meta-Analysis of Clinical Trials

Background: Familial hypercholesterolemia (FH) lead to significant adverse effects in coronary arteries. Mipomersen is a second-generation antisense oligonucleotide that inhibits the synthesis of apolipoprotein B-100, an essential component of low density lipoprotein (LDL), and thus decreases the pr...

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Detalles Bibliográficos
Autores principales:	Astaneh, Behrooz, Makhdami, Nima, Astaneh, Vala, Guyatt, Gordon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Systematic Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304130/ https://www.ncbi.nlm.nih.gov/pubmed/34357325 http://dx.doi.org/10.3390/jcdd8070082

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