Cargando…

Potential Therapies Targeting Metabolic Pathways in Cancer Stem Cells

Cancer stem cells (CSCs) are heterogeneous cells with stem cell-like properties that are responsible for therapeutic resistance, recurrence, and metastasis, and are the major cause for cancer treatment failure. Since CSCs have distinct metabolic characteristics that plays an important role in cancer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Yao-An, Chen, Chang-Cyuan, Chen, Bo-Jung, Wu, Yu-Ting, Juan, Jiun-Ru, Chen, Liang-Yun, Teng, Yueh-Chun, Wei, Yau-Huei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304173/ https://www.ncbi.nlm.nih.gov/pubmed/34359941 http://dx.doi.org/10.3390/cells10071772

Ejemplares similares

Frontier Review of the Molecular Mechanisms and Current Approaches of Stem Cell-Derived Exosomes
por: Chen, Liang-Yun, et al.
Publicado: (2023)

Resveratrol Impedes the Stemness, Epithelial-Mesenchymal Transition, and Metabolic Reprogramming of Cancer Stem Cells in Nasopharyngeal Carcinoma through p53 Activation
por: Shen, Yao-An, et al.
Publicado: (2013)

Association of chronic kidney disease with mortality risk in patients with lung cancer: a nationwide Taiwan population-based cohort study
por: Wei, Yu-Feng, et al.
Publicado: (2018)

Mitochondrial DNA Instability and Metabolic Shift in Human Cancers
por: Lee, Hsin-Chen, et al.
Publicado: (2009)

Therapeutic Targeting of Glutaminolysis as a Novel Strategy to Combat Cancer Stem Cells
por: Kao, Ting-Wan, et al.
Publicado: (2022)

Identification of Novel Targeting Sites of Calcineurin and CaMKII in Human Ca(V)3.2 T-Type Calcium Channel
por: Chang, Yu-Wang, et al.
Publicado: (2023)

Protective Effects of Licochalcone A Ameliorates Obesity and Non-Alcoholic Fatty Liver Disease Via Promotion of the Sirt-1/AMPK Pathway in Mice Fed a High-Fat Diet
por: Liou, Chian-Jiun, et al.
Publicado: (2019)

Involvement of collagen XVII in pluripotency gene expression and metabolic reprogramming of lung cancer stem cells
por: Hsu, Han-Shui, et al.
Publicado: (2020)

High Mitochondrial DNA Copy Number and Bioenergetic Function Are Associated with Tumor Invasion of Esophageal Squamous Cell Carcinoma Cell Lines
por: Lin, Chen-Sung, et al.
Publicado: (2012)

Tumor microenvironment-based screening repurposes drugs targeting cancer stem cells and cancer-associated fibroblasts
por: Lee, Pei-Jung, et al.
Publicado: (2021)

ROS and Oxidative Stress in Stem Cells
por: Cieślar-Pobuda, Artur, et al.
Publicado: (2017)

Mesenchymal Stem Cells in the Treatment of COVID-19
por: Guo, Bei-Cyuan, et al.
Publicado: (2023)

n-Butylidenephthalide (BP) Maintains Stem Cell Pluripotency by Activating Jak2/Stat3 Pathway and Increases the Efficiency of iPS Cells Generation
por: Liu, Shih-Ping, et al.
Publicado: (2012)

Metformin promotes apoptosis in hepatocellular carcinoma through the CEBPD-induced autophagy pathway
por: Tsai, Hsin-Hwa, et al.
Publicado: (2017)

Epicardial Adiposity in Relation to Metabolic Abnormality, Circulating Adipocyte FABP, and Preserved Ejection Fraction Heart Failure
por: Lin, Jiun-Lu, et al.
Publicado: (2021)

Stem Cell Therapy in Children with Traumatic Brain Injury
por: Lin, Wen-Ya, et al.
Publicado: (2023)

Overexpression of Insulin-Like Growth Factor 1 Enhanced the Osteogenic Capability of Aging Bone Marrow Mesenchymal Stem Cells
por: Chen, Ching-Yun, et al.
Publicado: (2017)

The Roles of Lipoprotein in Psoriasis
por: Shih, Chun-Ming, et al.
Publicado: (2020)

ATOH1/RFX1/RFX3 transcription factors facilitate the differentiation and characterisation of inner ear hair cell-like cells from patient-specific induced pluripotent stem cells harbouring A8344G mutation of mitochondrial DNA
por: Chen, Yen-Chun, et al.
Publicado: (2018)

Deep Learning–Based Brain Computed Tomography Image Classification with Hyperparameter Optimization through Transfer Learning for Stroke
por: Chen, Yung-Ting, et al.
Publicado: (2022)

Characterization and Aerosolization Performance of HydroxyPropyl-Beta-Cyclodextrin Particles Produced Using Supercritical Assisted Atomization
por: Wu, Hsien-Tsung, et al.
Publicado: (2021)

Metabolic Interventions in Tumor Immunity: Focus on Dual Pathway Inhibitors
por: Chen, Min, et al.
Publicado: (2023)

Esophageal Cancer Stem-like Cells Resist Ferroptosis-Induced Cell Death by Active Hsp27-GPX4 Pathway
por: Liu, Chen-Chi, et al.
Publicado: (2021)

Inhibitory Effects of Ursolic Acid on the Stemness and Progression of Human Breast Cancer Cells by Modulating Argonaute-2
por: Liao, Wen-Ling, et al.
Publicado: (2022)

Predictors of bacteremia in febrile infants under 3 months old in the pediatric emergency department
por: Guo, Bei-Cyuan, et al.
Publicado: (2023)

miR-103/107 prolong Wnt/β-catenin signaling and colorectal cancer stemness by targeting Axin2
por: Chen, Hsin-Yi, et al.
Publicado: (2019)

Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets
por: Wang, Bei, et al.
Publicado: (2021)

Metabolic Reprogramming in Response to Alterations of Mitochondrial DNA and Mitochondrial Dysfunction in Gastric Adenocarcinoma
por: Chang, Tzu-Ching, et al.
Publicado: (2022)

MiR-139 Modulates Cancer Stem Cell Function of Human Breast Cancer through Targeting CXCR4
por: Cheng, Chun-Wen, et al.
Publicado: (2021)

Hepatocellular carcinoma subtypes based on metabolic pathways reveals potential therapeutic targets
por: He, Zehua, et al.
Publicado: (2023)

Estrogen and/or Estrogen Receptor α Inhibits BNIP3-Induced Apoptosis and Autophagy in H9c2 Cardiomyoblast Cells
por: Chen, Bih-Cheng, et al.
Publicado: (2018)

The STIM1-Orai1 pathway of store-operated Ca(2+) entry controls the checkpoint in cell cycle G1/S transition
por: Chen, Yun-Wen, et al.
Publicado: (2016)

Bypassing the EPR effect with a nanomedicine harboring a sustained-release function allows better tumor control
por: Shen, Yao An, et al.
Publicado: (2015)

Isolation and Characterization of a Novel Strain of Mesenchymal Stem Cells from Mouse Umbilical Cord: Potential Application in Cell-Based Therapy
por: Li, Wen-Wen, et al.
Publicado: (2013)

Breast Cancer with Increased Drug Resistance, Invasion Ability, and Cancer Stem Cell Properties through Metabolism Reprogramming
por: Chong, Kian-Hwee, et al.
Publicado: (2022)

Site-specific Conjugation of 6 DOTA Chelators to a CA19-9-targeting scFv-Fc Antibody for Imaging and Therapy
por: Chen, Li-An, et al.
Publicado: (2023)

Activated Human Nasal Epithelial Cells Modulate Specific Antibody Response against Bacterial or Viral Antigens
por: Yeh, Chiou-Yueh, et al.
Publicado: (2013)

Immunomagnetic Reduction Detects Plasma Aβ(1–42) Levels as a Potential Dominant Indicator Predicting Cognitive Decline
por: Yang, Shieh-Yueh, et al.
Publicado: (2020)

Adipose‑derived stem cell‑mediated alphastatin targeting delivery system inhibits angiogenesis and tumor growth in glioma
por: Liang, Chen, et al.
Publicado: (2023)

Characterization of ROS Metabolic Equilibrium Reclassifies Pan-Cancer Samples and Guides Pathway Targeting Therapy
por: Shen, Shuai, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gq23jhu5l987o522u6jp8m1t72