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Preconditioning-Activated AKT Controls Neuronal Tolerance to Ischemia through the MDM2–p53 Pathway

One of the most important mechanisms of preconditioning-mediated neuroprotection is the attenuation of cell apoptosis, inducing brain tolerance after a subsequent injurious ischemia. In this context, the antiapoptotic PI3K/AKT signaling pathway plays a key role by regulating cell differentiation and...

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Detalles Bibliográficos
Autores principales:	Barrio, Emilia, Vecino, Rebeca, Sánchez-Morán, Irene, Rodríguez, Cristina, Suárez-Pindado, Alberto, Bolaños, Juan P., Almeida, Angeles, Delgado-Esteban, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304232/ https://www.ncbi.nlm.nih.gov/pubmed/34298892 http://dx.doi.org/10.3390/ijms22147275

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