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Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men

Visceral adipose tissue (VAT) has high metabolic activity and secretes a larger number of adipokines that are related to the inflammatory process. Quantifying VAT could estimate the risk of developing Metabolic Syndrome (MetS). This study was designed to determine the VAT cut-off points assessed by...

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Autores principales: da Rosa, Samir Ezequiel, Costa, Amina Chain, Fortes, Marcos S. R., Marson, Runer Augusto, Neves, Eduardo Borba, Rodrigues, Laercio Camilo, Ferreira, Paula Fernandez, Filho, Jose Fernandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304366/
https://www.ncbi.nlm.nih.gov/pubmed/34356264
http://dx.doi.org/10.3390/healthcare9070886
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author da Rosa, Samir Ezequiel
Costa, Amina Chain
Fortes, Marcos S. R.
Marson, Runer Augusto
Neves, Eduardo Borba
Rodrigues, Laercio Camilo
Ferreira, Paula Fernandez
Filho, Jose Fernandes
author_facet da Rosa, Samir Ezequiel
Costa, Amina Chain
Fortes, Marcos S. R.
Marson, Runer Augusto
Neves, Eduardo Borba
Rodrigues, Laercio Camilo
Ferreira, Paula Fernandez
Filho, Jose Fernandes
author_sort da Rosa, Samir Ezequiel
collection PubMed
description Visceral adipose tissue (VAT) has high metabolic activity and secretes a larger number of adipokines that are related to the inflammatory process. Quantifying VAT could estimate the risk of developing Metabolic Syndrome (MetS). This study was designed to determine the VAT cut-off points assessed by DXA associated with MetS in military men. In total, 270 (37.5 ± 6.9 years) military men from the Brazilian Army (BA) participated in the study. Anthropometric measurements, assessment of body composition by dual X-ray absorptiometry (DXA), hemodynamics and biochemical tests were performed. The Student’s t test, independent samples, Person’s correlation, ROC curve, Youden Index and positive (PPV) and negative predictive value (NPV) were used. The MetS prevalence was 27.4%, which means that 74 (38.0 ± 7.3 years) military men had at least three risk factors of MetS present. The cutoff point of VAT with the highest balance between sensitivity (77.0%) and specificity (69.9%) was 1025.0 cm(3) (1086.0 g). An area on the ROC curve was 0.801 (p < 0.000), which was very good precision. VAT ≥ 1025.0 cm(3) (1086.0 g) is associated with the risk factors of MetS and is, therefore, a predictor of the disease with good indicators of sensitivity and specificity and a robust indicator of MetS.
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spelling pubmed-83043662021-07-25 Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men da Rosa, Samir Ezequiel Costa, Amina Chain Fortes, Marcos S. R. Marson, Runer Augusto Neves, Eduardo Borba Rodrigues, Laercio Camilo Ferreira, Paula Fernandez Filho, Jose Fernandes Healthcare (Basel) Article Visceral adipose tissue (VAT) has high metabolic activity and secretes a larger number of adipokines that are related to the inflammatory process. Quantifying VAT could estimate the risk of developing Metabolic Syndrome (MetS). This study was designed to determine the VAT cut-off points assessed by DXA associated with MetS in military men. In total, 270 (37.5 ± 6.9 years) military men from the Brazilian Army (BA) participated in the study. Anthropometric measurements, assessment of body composition by dual X-ray absorptiometry (DXA), hemodynamics and biochemical tests were performed. The Student’s t test, independent samples, Person’s correlation, ROC curve, Youden Index and positive (PPV) and negative predictive value (NPV) were used. The MetS prevalence was 27.4%, which means that 74 (38.0 ± 7.3 years) military men had at least three risk factors of MetS present. The cutoff point of VAT with the highest balance between sensitivity (77.0%) and specificity (69.9%) was 1025.0 cm(3) (1086.0 g). An area on the ROC curve was 0.801 (p < 0.000), which was very good precision. VAT ≥ 1025.0 cm(3) (1086.0 g) is associated with the risk factors of MetS and is, therefore, a predictor of the disease with good indicators of sensitivity and specificity and a robust indicator of MetS. MDPI 2021-07-14 /pmc/articles/PMC8304366/ /pubmed/34356264 http://dx.doi.org/10.3390/healthcare9070886 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
da Rosa, Samir Ezequiel
Costa, Amina Chain
Fortes, Marcos S. R.
Marson, Runer Augusto
Neves, Eduardo Borba
Rodrigues, Laercio Camilo
Ferreira, Paula Fernandez
Filho, Jose Fernandes
Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men
title Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men
title_full Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men
title_fullStr Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men
title_full_unstemmed Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men
title_short Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men
title_sort cut-off points of visceral adipose tissue associated with metabolic syndrome in military men
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304366/
https://www.ncbi.nlm.nih.gov/pubmed/34356264
http://dx.doi.org/10.3390/healthcare9070886
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