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Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men
Visceral adipose tissue (VAT) has high metabolic activity and secretes a larger number of adipokines that are related to the inflammatory process. Quantifying VAT could estimate the risk of developing Metabolic Syndrome (MetS). This study was designed to determine the VAT cut-off points assessed by...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304366/ https://www.ncbi.nlm.nih.gov/pubmed/34356264 http://dx.doi.org/10.3390/healthcare9070886 |
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author | da Rosa, Samir Ezequiel Costa, Amina Chain Fortes, Marcos S. R. Marson, Runer Augusto Neves, Eduardo Borba Rodrigues, Laercio Camilo Ferreira, Paula Fernandez Filho, Jose Fernandes |
author_facet | da Rosa, Samir Ezequiel Costa, Amina Chain Fortes, Marcos S. R. Marson, Runer Augusto Neves, Eduardo Borba Rodrigues, Laercio Camilo Ferreira, Paula Fernandez Filho, Jose Fernandes |
author_sort | da Rosa, Samir Ezequiel |
collection | PubMed |
description | Visceral adipose tissue (VAT) has high metabolic activity and secretes a larger number of adipokines that are related to the inflammatory process. Quantifying VAT could estimate the risk of developing Metabolic Syndrome (MetS). This study was designed to determine the VAT cut-off points assessed by DXA associated with MetS in military men. In total, 270 (37.5 ± 6.9 years) military men from the Brazilian Army (BA) participated in the study. Anthropometric measurements, assessment of body composition by dual X-ray absorptiometry (DXA), hemodynamics and biochemical tests were performed. The Student’s t test, independent samples, Person’s correlation, ROC curve, Youden Index and positive (PPV) and negative predictive value (NPV) were used. The MetS prevalence was 27.4%, which means that 74 (38.0 ± 7.3 years) military men had at least three risk factors of MetS present. The cutoff point of VAT with the highest balance between sensitivity (77.0%) and specificity (69.9%) was 1025.0 cm(3) (1086.0 g). An area on the ROC curve was 0.801 (p < 0.000), which was very good precision. VAT ≥ 1025.0 cm(3) (1086.0 g) is associated with the risk factors of MetS and is, therefore, a predictor of the disease with good indicators of sensitivity and specificity and a robust indicator of MetS. |
format | Online Article Text |
id | pubmed-8304366 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83043662021-07-25 Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men da Rosa, Samir Ezequiel Costa, Amina Chain Fortes, Marcos S. R. Marson, Runer Augusto Neves, Eduardo Borba Rodrigues, Laercio Camilo Ferreira, Paula Fernandez Filho, Jose Fernandes Healthcare (Basel) Article Visceral adipose tissue (VAT) has high metabolic activity and secretes a larger number of adipokines that are related to the inflammatory process. Quantifying VAT could estimate the risk of developing Metabolic Syndrome (MetS). This study was designed to determine the VAT cut-off points assessed by DXA associated with MetS in military men. In total, 270 (37.5 ± 6.9 years) military men from the Brazilian Army (BA) participated in the study. Anthropometric measurements, assessment of body composition by dual X-ray absorptiometry (DXA), hemodynamics and biochemical tests were performed. The Student’s t test, independent samples, Person’s correlation, ROC curve, Youden Index and positive (PPV) and negative predictive value (NPV) were used. The MetS prevalence was 27.4%, which means that 74 (38.0 ± 7.3 years) military men had at least three risk factors of MetS present. The cutoff point of VAT with the highest balance between sensitivity (77.0%) and specificity (69.9%) was 1025.0 cm(3) (1086.0 g). An area on the ROC curve was 0.801 (p < 0.000), which was very good precision. VAT ≥ 1025.0 cm(3) (1086.0 g) is associated with the risk factors of MetS and is, therefore, a predictor of the disease with good indicators of sensitivity and specificity and a robust indicator of MetS. MDPI 2021-07-14 /pmc/articles/PMC8304366/ /pubmed/34356264 http://dx.doi.org/10.3390/healthcare9070886 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article da Rosa, Samir Ezequiel Costa, Amina Chain Fortes, Marcos S. R. Marson, Runer Augusto Neves, Eduardo Borba Rodrigues, Laercio Camilo Ferreira, Paula Fernandez Filho, Jose Fernandes Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men |
title | Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men |
title_full | Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men |
title_fullStr | Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men |
title_full_unstemmed | Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men |
title_short | Cut-Off Points of Visceral Adipose Tissue Associated with Metabolic Syndrome in Military Men |
title_sort | cut-off points of visceral adipose tissue associated with metabolic syndrome in military men |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304366/ https://www.ncbi.nlm.nih.gov/pubmed/34356264 http://dx.doi.org/10.3390/healthcare9070886 |
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