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The Anti-VEGF(R) Drug Discovery Legacy: Improving Attrition Rates by Breaking the Vicious Cycle of Angiogenesis in Cancer

SIMPLE SUMMARY: Several anti-angiogenic drugs have been approved for cancer treatment, alone or in combination with other anti-tumoral agents. Angiogenesis inhibitors cause drug resistance, metastasis formation, and reduced delivery of chemotherapeutic agents, as a consequence of decrease of tumor v...

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Detalles Bibliográficos
Autores principales:	Ribatti, Domenico, Solimando, Antonio Giovanni, Pezzella, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304542/ https://www.ncbi.nlm.nih.gov/pubmed/34298648 http://dx.doi.org/10.3390/cancers13143433

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