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Age-Dependent Hippocampal Proteomics in the APP/PS1 Alzheimer Mouse Model: A Comparative Analysis with Classical SWATH/DIA and directDIA Approaches
Alzheimer’s disease (AD) is the most common neurodegenerative disorder in the human population, for which there is currently no cure. The cause of AD is unknown; however, the toxic effects of amyloid-β (Aβ) are believed to play a role in its onset. To investigate this, we examined changes in global...
Autores principales: | van der Spek, Sophie J. F., Gonzalez-Lozano, Miguel A., Koopmans, Frank, Miedema, Suzanne S. M., Paliukhovich, Iryna, Smit, August B., Li, Ka Wan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304546/ https://www.ncbi.nlm.nih.gov/pubmed/34202490 http://dx.doi.org/10.3390/cells10071588 |
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