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Reconstitution of Functional Integrin αIIbβ3 and Its Activation in Plasma Membrane-Mimetic Lipid Environments

The study of the platelet receptor integrin αIIbβ3 in a membrane-mimetic environment without interfering signalling pathways is crucial to understand protein structure and dynamics. Our understanding of this receptor and its sequential activation steps has been tremendously progressing using structu...

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Detalles Bibliográficos
Autores principales: Janke, Una, Mitlehner, Alexandra, Weide, Aileen, Gutmann, Theresia, Delcea, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304682/
https://www.ncbi.nlm.nih.gov/pubmed/34209233
http://dx.doi.org/10.3390/membranes11070499