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Reconstitution of Functional Integrin αIIbβ3 and Its Activation in Plasma Membrane-Mimetic Lipid Environments
The study of the platelet receptor integrin αIIbβ3 in a membrane-mimetic environment without interfering signalling pathways is crucial to understand protein structure and dynamics. Our understanding of this receptor and its sequential activation steps has been tremendously progressing using structu...
Autores principales: | Janke, Una, Mitlehner, Alexandra, Weide, Aileen, Gutmann, Theresia, Delcea, Mihaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304682/ https://www.ncbi.nlm.nih.gov/pubmed/34209233 http://dx.doi.org/10.3390/membranes11070499 |
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