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Stress-Inducible Gene Atf3 Dictates a Dichotomous Macrophage Activity in Chemotherapy-Enhanced Lung Colonization

Previously, we showed that chemotherapy paradoxically exacerbated cancer cell colonization at the secondary site in a manner dependent on Atf3, a stress-inducible gene, in the non-cancer host cells. Here, we present evidence that this phenotype is established at an early stage of colonization within...

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Detalles Bibliográficos
Autores principales: Middleton, Justin D., Fehlman, Jared, Sivakumar, Subhakeertana, Stover, Daniel G., Hai, Tsonwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304704/
https://www.ncbi.nlm.nih.gov/pubmed/34298975
http://dx.doi.org/10.3390/ijms22147356