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Solvent Screening for Solubility Enhancement of Theophylline in Neat, Binary and Ternary NADES Solvents: New Measurements and Ensemble Machine Learning

Theophylline, a typical representative of active pharmaceutical ingredients, was selected to study the characteristics of experimental and theoretical solubility measured at 25 °C in a broad range of solvents, including neat, binary mixtures and ternary natural deep eutectics (NADES) prepared with c...

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Detalles Bibliográficos
Autores principales: Cysewski, Piotr, Jeliński, Tomasz, Cymerman, Patryk, Przybyłek, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304713/
https://www.ncbi.nlm.nih.gov/pubmed/34298966
http://dx.doi.org/10.3390/ijms22147347