Cargando…

Effects of Automation on Sustainability of Immunohistochemistry Laboratory

The COVID-19 pandemic that hit the world recently caused numerous changes affecting the health system in every department. Reduced staff numbers, mostly due to illness, led to an increase in automation at every stage of laboratory work. The immunohistochemistry (IHC) laboratory conducts a high volum...

Descripción completa

Detalles Bibliográficos
Autores principales: Đorđević, Marija, Životić, Maja, Radojević Škodrić, Sanja, Nešović Ostojić, Jelena, Marković Lipkovski, Jasmina, Filipović, Jelena, Ćirović, Sanja, Kovačević, Sanjin, Dunđerović, Duško
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304755/
https://www.ncbi.nlm.nih.gov/pubmed/34356244
http://dx.doi.org/10.3390/healthcare9070866
_version_ 1783727411364364288
author Đorđević, Marija
Životić, Maja
Radojević Škodrić, Sanja
Nešović Ostojić, Jelena
Marković Lipkovski, Jasmina
Filipović, Jelena
Ćirović, Sanja
Kovačević, Sanjin
Dunđerović, Duško
author_facet Đorđević, Marija
Životić, Maja
Radojević Škodrić, Sanja
Nešović Ostojić, Jelena
Marković Lipkovski, Jasmina
Filipović, Jelena
Ćirović, Sanja
Kovačević, Sanjin
Dunđerović, Duško
author_sort Đorđević, Marija
collection PubMed
description The COVID-19 pandemic that hit the world recently caused numerous changes affecting the health system in every department. Reduced staff numbers, mostly due to illness, led to an increase in automation at every stage of laboratory work. The immunohistochemistry (IHC) laboratory conducts a high volume of slide staining every day. Therefore, we analyzed time and total costs required to obtain IHC slides in both the manual and automated way, comparing their efficiency by processing the same sample volume (48 microscope slides—the maximum capacity that an automated immunostainer—DAKO, Autostainer Link 48, Part No AS48030—can process over a single cycle). The total IHC procedure time to run 48 slides manually by one technician was 460 min, while the automated process finished a cycle within 390 min (15.22% less time). The final cost of a single manual IHC slide was 12.26 EUR and 7.69 EUR for slides labeled in the automated immunostainer, which reduced final costs by 37.27%. Thus, automation of the IHC procedure reduces the time and costs of the IHC process, contributing significantly to the sustainability of the healthcare system during the COVID-19 pandemic, overcoming insufficient human resources.
format Online
Article
Text
id pubmed-8304755
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-83047552021-07-25 Effects of Automation on Sustainability of Immunohistochemistry Laboratory Đorđević, Marija Životić, Maja Radojević Škodrić, Sanja Nešović Ostojić, Jelena Marković Lipkovski, Jasmina Filipović, Jelena Ćirović, Sanja Kovačević, Sanjin Dunđerović, Duško Healthcare (Basel) Article The COVID-19 pandemic that hit the world recently caused numerous changes affecting the health system in every department. Reduced staff numbers, mostly due to illness, led to an increase in automation at every stage of laboratory work. The immunohistochemistry (IHC) laboratory conducts a high volume of slide staining every day. Therefore, we analyzed time and total costs required to obtain IHC slides in both the manual and automated way, comparing their efficiency by processing the same sample volume (48 microscope slides—the maximum capacity that an automated immunostainer—DAKO, Autostainer Link 48, Part No AS48030—can process over a single cycle). The total IHC procedure time to run 48 slides manually by one technician was 460 min, while the automated process finished a cycle within 390 min (15.22% less time). The final cost of a single manual IHC slide was 12.26 EUR and 7.69 EUR for slides labeled in the automated immunostainer, which reduced final costs by 37.27%. Thus, automation of the IHC procedure reduces the time and costs of the IHC process, contributing significantly to the sustainability of the healthcare system during the COVID-19 pandemic, overcoming insufficient human resources. MDPI 2021-07-08 /pmc/articles/PMC8304755/ /pubmed/34356244 http://dx.doi.org/10.3390/healthcare9070866 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Đorđević, Marija
Životić, Maja
Radojević Škodrić, Sanja
Nešović Ostojić, Jelena
Marković Lipkovski, Jasmina
Filipović, Jelena
Ćirović, Sanja
Kovačević, Sanjin
Dunđerović, Duško
Effects of Automation on Sustainability of Immunohistochemistry Laboratory
title Effects of Automation on Sustainability of Immunohistochemistry Laboratory
title_full Effects of Automation on Sustainability of Immunohistochemistry Laboratory
title_fullStr Effects of Automation on Sustainability of Immunohistochemistry Laboratory
title_full_unstemmed Effects of Automation on Sustainability of Immunohistochemistry Laboratory
title_short Effects of Automation on Sustainability of Immunohistochemistry Laboratory
title_sort effects of automation on sustainability of immunohistochemistry laboratory
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304755/
https://www.ncbi.nlm.nih.gov/pubmed/34356244
http://dx.doi.org/10.3390/healthcare9070866
work_keys_str_mv AT đorđevicmarija effectsofautomationonsustainabilityofimmunohistochemistrylaboratory
AT zivoticmaja effectsofautomationonsustainabilityofimmunohistochemistrylaboratory
AT radojevicskodricsanja effectsofautomationonsustainabilityofimmunohistochemistrylaboratory
AT nesovicostojicjelena effectsofautomationonsustainabilityofimmunohistochemistrylaboratory
AT markoviclipkovskijasmina effectsofautomationonsustainabilityofimmunohistochemistrylaboratory
AT filipovicjelena effectsofautomationonsustainabilityofimmunohistochemistrylaboratory
AT cirovicsanja effectsofautomationonsustainabilityofimmunohistochemistrylaboratory
AT kovacevicsanjin effectsofautomationonsustainabilityofimmunohistochemistrylaboratory
AT dunđerovicdusko effectsofautomationonsustainabilityofimmunohistochemistrylaboratory