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The Marine-Derived Natural Product Epiloliolide Isolated from Sargassum horneri Regulates NLRP3 via PKA/CREB, Promoting Proliferation and Anti-Inflammatory Effects of Human Periodontal Ligament Cells

Currently, periodontitis treatment relies on surgical operations, anti-inflammatory agents, or antibiotics. However, these treatments cause pain and side effects, resulting in a poor prognosis. Therefore, in this study, we evaluated the impact of the compound epiloliolide isolated from Sargassum hor...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Nam, Nabende, Woguti Yvonne, Jeong, Hyeyoon, Hahn, Dongyup, Jeong, Gil-Saeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304756/
https://www.ncbi.nlm.nih.gov/pubmed/34356813
http://dx.doi.org/10.3390/md19070388