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Development of an Androgen Receptor Inhibitor Targeting the N-Terminal Domain of Androgen Receptor for Treatment of Castration Resistant Prostate Cancer
SIMPLE SUMMARY: In almost all patients, the proliferation and growth of prostate cancer is driven by the androgen receptor. Given this critical role, inhibiting the androgen receptor is the standard of care following surgery or radiotherapy. However, the effectiveness of current anti-androgen therap...
Autores principales: | Ban, Fuqiang, Leblanc, Eric, Cavga, Ayse Derya, Huang, Chia-Chi Flora, Flory, Mark R., Zhang, Fan, Chang, Matthew E. K., Morin, Hélène, Lallous, Nada, Singh, Kriti, Gleave, Martin E., Mohammed, Hisham, Rennie, Paul S., Lack, Nathan A., Cherkasov, Artem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304761/ https://www.ncbi.nlm.nih.gov/pubmed/34298700 http://dx.doi.org/10.3390/cancers13143488 |
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