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Evaluation of Prognostic Factors for Palatal Fistulae after Cleft Lip and Palate Surgery in a North-Western Romanian Population over a 10-Year Period

Cleft lip and palate is the most frequent birth anomaly, with increasing reported rates of complications, such as palate fistulae. Current studies concerning the occurrence rate of cleft lip and palate (CLP) report 2 to 10 cases in 10,000 births. The purpose of this study was to investigate the exis...

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Autores principales: Opris, Daiana Antoaneta, Opris, Horia, Dinu, Cristian, Bran, Simion, Baciut, Grigore, Armencea, Gabriel, Mitre, Ileana, Colosi, Horatiu Alexandru, Baciut, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304784/
https://www.ncbi.nlm.nih.gov/pubmed/34299755
http://dx.doi.org/10.3390/ijerph18147305
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author Opris, Daiana Antoaneta
Opris, Horia
Dinu, Cristian
Bran, Simion
Baciut, Grigore
Armencea, Gabriel
Mitre, Ileana
Colosi, Horatiu Alexandru
Baciut, Mihaela
author_facet Opris, Daiana Antoaneta
Opris, Horia
Dinu, Cristian
Bran, Simion
Baciut, Grigore
Armencea, Gabriel
Mitre, Ileana
Colosi, Horatiu Alexandru
Baciut, Mihaela
author_sort Opris, Daiana Antoaneta
collection PubMed
description Cleft lip and palate is the most frequent birth anomaly, with increasing reported rates of complications, such as palate fistulae. Current studies concerning the occurrence rate of cleft lip and palate (CLP) report 2 to 10 cases in 10,000 births. The purpose of this study was to investigate the existence of factors that could predict the occurrence of fistulae after cleft lip and palate surgery. A retrospective study was performed by collecting and analyzing data from all patients who were operated for cleft lip and/or palate in the Maxillo-Facial Department of the Emergency Clinical County Hospital of Cluj-Napoca, Romania, between 2010 and 2020. We investigated the existing evidence for possible links between the number of fistulae observed after the primary palatoplasty and the age at which the primary palatoplasty was performed, the sex of the patient, the type of cleft, the timing of the surgical corrections, and the presence of comorbidities. A total of 137 cases were included for analysis. A significant link between the number of fistulae and the type of cleft was found (with fistulae occurring more frequently after the surgical correction of CLP—p < 0.001). No evidence was found for the existence of significant links between the number of fistulae and the patient’s sex, the timing of surgery, or the presence of comorbidities. This study concluded that the incidence of palatal fistulae appears to be influenced by the type of cleft (CLP), but not by the sex of the patient, the timing of surgery, or the presence of comorbidities.
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spelling pubmed-83047842021-07-25 Evaluation of Prognostic Factors for Palatal Fistulae after Cleft Lip and Palate Surgery in a North-Western Romanian Population over a 10-Year Period Opris, Daiana Antoaneta Opris, Horia Dinu, Cristian Bran, Simion Baciut, Grigore Armencea, Gabriel Mitre, Ileana Colosi, Horatiu Alexandru Baciut, Mihaela Int J Environ Res Public Health Article Cleft lip and palate is the most frequent birth anomaly, with increasing reported rates of complications, such as palate fistulae. Current studies concerning the occurrence rate of cleft lip and palate (CLP) report 2 to 10 cases in 10,000 births. The purpose of this study was to investigate the existence of factors that could predict the occurrence of fistulae after cleft lip and palate surgery. A retrospective study was performed by collecting and analyzing data from all patients who were operated for cleft lip and/or palate in the Maxillo-Facial Department of the Emergency Clinical County Hospital of Cluj-Napoca, Romania, between 2010 and 2020. We investigated the existing evidence for possible links between the number of fistulae observed after the primary palatoplasty and the age at which the primary palatoplasty was performed, the sex of the patient, the type of cleft, the timing of the surgical corrections, and the presence of comorbidities. A total of 137 cases were included for analysis. A significant link between the number of fistulae and the type of cleft was found (with fistulae occurring more frequently after the surgical correction of CLP—p < 0.001). No evidence was found for the existence of significant links between the number of fistulae and the patient’s sex, the timing of surgery, or the presence of comorbidities. This study concluded that the incidence of palatal fistulae appears to be influenced by the type of cleft (CLP), but not by the sex of the patient, the timing of surgery, or the presence of comorbidities. MDPI 2021-07-08 /pmc/articles/PMC8304784/ /pubmed/34299755 http://dx.doi.org/10.3390/ijerph18147305 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Opris, Daiana Antoaneta
Opris, Horia
Dinu, Cristian
Bran, Simion
Baciut, Grigore
Armencea, Gabriel
Mitre, Ileana
Colosi, Horatiu Alexandru
Baciut, Mihaela
Evaluation of Prognostic Factors for Palatal Fistulae after Cleft Lip and Palate Surgery in a North-Western Romanian Population over a 10-Year Period
title Evaluation of Prognostic Factors for Palatal Fistulae after Cleft Lip and Palate Surgery in a North-Western Romanian Population over a 10-Year Period
title_full Evaluation of Prognostic Factors for Palatal Fistulae after Cleft Lip and Palate Surgery in a North-Western Romanian Population over a 10-Year Period
title_fullStr Evaluation of Prognostic Factors for Palatal Fistulae after Cleft Lip and Palate Surgery in a North-Western Romanian Population over a 10-Year Period
title_full_unstemmed Evaluation of Prognostic Factors for Palatal Fistulae after Cleft Lip and Palate Surgery in a North-Western Romanian Population over a 10-Year Period
title_short Evaluation of Prognostic Factors for Palatal Fistulae after Cleft Lip and Palate Surgery in a North-Western Romanian Population over a 10-Year Period
title_sort evaluation of prognostic factors for palatal fistulae after cleft lip and palate surgery in a north-western romanian population over a 10-year period
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304784/
https://www.ncbi.nlm.nih.gov/pubmed/34299755
http://dx.doi.org/10.3390/ijerph18147305
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