Cargando…

Gene Transcription as a Therapeutic Target in Leukemia

Blood malignancies often arise from undifferentiated hematopoietic stem cells or partially differentiated stem-like cells. A tight balance of multipotency and differentiation, cell division, and quiescence underlying normal hematopoiesis requires a special program governed by the transcriptional mac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khamidullina, Alvina I., Varlamova, Ekaterina A., Hammoud, Nour Alhuda, Yastrebova, Margarita A., Bruter, Alexandra V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304797/ https://www.ncbi.nlm.nih.gov/pubmed/34298959 http://dx.doi.org/10.3390/ijms22147340

Ejemplares similares

Comparison of the mRNA expression profile of B‐cell receptor components in normal CD5‐high B‐lymphocytes and chronic lymphocytic leukemia: a key role of ZAP70
por: Gladkikh, Aleena A., et al.
Publicado: (2017)

Super-Enhancers in the Regulation of Gene Transcription: General Aspects and Antitumor Targets
por: Bruter, A. V., et al.
Publicado: (2021)

New Approach for Studying of Isoforms and High-Homology Proteins in Mammalian Cells
por: Soshnikova, Nataliya V., et al.
Publicado: (2023)

Limitations of Tamoxifen Application for In Vivo Genome Editing Using Cre/ER(T2) System
por: Ilchuk, Leonid A., et al.
Publicado: (2022)

Snail-Family Proteins: Role in Carcinogenesis and Prospects for Antitumor Therapy
por: Yastrebova, M. A., et al.
Publicado: (2021)

Therapeutic Potential and Main Methods of Obtaining Selenium Nanoparticles
por: Varlamova, Elena G., et al.
Publicado: (2021)

Akt and Src mediate the photocrosslinked fibroin-induced neural differentiation.
por: Moysenovich, Anastasia M., et al.
Publicado: (2020)

A novel chromatin-remodeling complex variant, dcPBAF, is involved in maintaining transcription in differentiated neurons
por: Soshnikova, Nataliya V., et al.
Publicado: (2023)

Targeting General Transcriptional Machinery as a Therapeutic Strategy for Adult T-Cell Leukemia
por: Wong, Regina Wan Ju, et al.
Publicado: (2018)

MNK Proteins as Therapeutic Targets in Leukemia
por: Mazewski, Candice, et al.
Publicado: (2023)

Therapeutic targeting of CK2 in acute and chronic leukemias
por: Buontempo, F, et al.
Publicado: (2018)

A Unique Prototypic Device for Radiation Therapy: The p53-Independent Antiproliferative Effect of Neutron Radiation
por: Yurkov, D. I., et al.
Publicado: (2019)

The Hedgehog Pathway as a Therapeutic Target in Chronic Myeloid Leukemia
por: Wu, Andrew, et al.
Publicado: (2023)

Cyclophilin A as a Pro-Inflammatory Factor Exhibits Embryotoxic and Teratogenic Effects during Fetal Organogenesis
por: Kalinina, Anastasiia, et al.
Publicado: (2023)

Rapid-onset obesity, hypoventilation, hypothalamic dysfunction, autonomic dysregulation and neuroendocrine tumor syndrome with a homogenous enlargement of the pituitary gland: a case report
por: Aljabban, Lama, et al.
Publicado: (2016)

Nuclear Receptors as Potential Therapeutic Targets for Myeloid Leukemia
por: Pan, Pan, et al.
Publicado: (2020)

Therapeutic Targeting of Acute Myeloid Leukemia by Gemtuzumab Ozogamicin
por: Gottardi, Michele, et al.
Publicado: (2021)

Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An Update
por: Evangelisti, Camilla, et al.
Publicado: (2018)

The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias
por: Martelli, Alberto M., et al.
Publicado: (2020)

Transcription Inhibition as a Therapeutic Target for Cancer
por: Stellrecht, Christine M., et al.
Publicado: (2011)

Therapeutic targeting of transcriptional cyclin-dependent kinases
por: Galbraith, Matthew D., et al.
Publicado: (2018)

Transcription factors are potential therapeutic targets in epilepsy
por: Sun, Qihan, et al.
Publicado: (2022)

Emerging therapeutic targets in myeloproliferative neoplasms and peripheral T-cell leukemia and lymphomas
por: Orlova, Anna, et al.
Publicado: (2017)

SOXC Transcription Factors as Diagnostic Biomarkers and Therapeutic Targets for Arthritis
por: Ahmed, Emad A., et al.
Publicado: (2023)

Genomic Abnormalities as Biomarkers and Therapeutic Targets in Acute Myeloid Leukemia
por: Ribeiro, Sara, et al.
Publicado: (2021)

Chronic myeloid leukemia stem cells: targeting therapeutic implications
por: Mojtahedi, Hanieh, et al.
Publicado: (2021)

Lysosomes in acute myeloid leukemia: potential therapeutic targets?
por: Rafiq, Sreoshee, et al.
Publicado: (2021)

Genetically Engineered Mice Unveil In Vivo Roles of the Mediator Complex
por: Ilchuk, Leonid A., et al.
Publicado: (2023)

Assessment of the effectiveness of psychosocial rehabilitation in schizophrenia patients using biological markers
por: Zozulya, S., et al.
Publicado: (2021)

Chronic eosinophilic leukemia with FIP1L1-PDGFRA transcripts after occupational and therapeutic exposure to radiation
por: Balatzenko, Gueorgui, et al.
Publicado: (2011)

Transcription Factors as Therapeutic Targets in Chronic Kidney Disease
por: Hishikawa, Akihito, et al.
Publicado: (2018)

Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer
por: Yang, Fan, et al.
Publicado: (2022)

Impairment of motivation in patients with schizophrenia and the development of a program for their psychosocial treatment
por: Mitikhin, V., et al.
Publicado: (2021)

Genetic Alterations and Therapeutic Targeting of Philadelphia-Like Acute Lymphoblastic Leukemia
por: Iacobucci, Ilaria, et al.
Publicado: (2021)

The Promising Role of Non-Coding RNAs as Biomarkers and Therapeutic Targets for Leukemia
por: Ghazimoradi, Mohammad H., et al.
Publicado: (2023)

Human Coronavirus Cell Receptors Provide Challenging Therapeutic Targets
por: López-Cortés, Georgina I., et al.
Publicado: (2023)

Direct and Indirect Targeting of HOXA9 Transcription Factor in Acute Myeloid Leukemia
por: Lambert, Mélanie, et al.
Publicado: (2019)

Transcriptional Regulation of Genes by Ikaros Tumor Suppressor in Acute Lymphoblastic Leukemia
por: Dhanyamraju, Pavan Kumar, et al.
Publicado: (2020)

Transcriptional addiction in mixed lineage leukemia: new avenues for target therapies
por: Xiao, Ruijing, et al.
Publicado: (2019)

Identification of Potential Therapeutic Targets on the Level of DNA/mRNAs, Proteins and Metabolites: A Systematic Mapping Review of Scientific Texts’ Fragments from Open Targets
por: Pogodin, Pavel V., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hmm1q2kta0eeomb9nju20139vv