Cargando…

Expression of DDX11 and DNM1L at the 12p11 Locus Modulates Systemic Lupus Erythematosus Susceptibility

Objectives: This study employed genetic and functional analyses using OASIS meta-analysis of multiple existing GWAS and gene-expression datasets to identify novel SLE genes. Methods: Four hundred and ten genes were mapped using SNIPPER to 30 SLE GWAS loci and investigated for expression in three SLE...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saeed, Mohammad, Ibáñez-Costa, Alejandro, Patiño-Trives, Alejandra María, Muñoz-Barrera, Laura, Collantes Estévez, Eduardo, Aguirre, María Ángeles, López-Pedrera, Chary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304828/ https://www.ncbi.nlm.nih.gov/pubmed/34299244 http://dx.doi.org/10.3390/ijms22147624

Ejemplares similares

New Biomarkers for Atherothrombosis in Antiphospholipid Syndrome: Genomics and Epigenetics Approaches
por: Lopez-Pedrera, Chary, et al.
Publicado: (2019)

Early restoration of immune and vascular phenotypes in systemic lupus erythematosus and rheumatoid arthritis patients after B cell depletion
por: Pérez‐Sánchez, Carlos, et al.
Publicado: (2019)

Role of microRNAs in the Development of Cardiovascular Disease in Systemic Autoimmune Disorders
por: Lopez-Pedrera, Chary, et al.
Publicado: (2020)

Accelerated Atherosclerosis in Systemic Lupus Erythematosus: Role of Proinflammatory Cytokines and Therapeutic Approaches
por: López-Pedrera, Chary, et al.
Publicado: (2010)

Effects of Biological Therapies on Molecular Features of Rheumatoid Arthritis
por: Lopez-Pedrera, Chary, et al.
Publicado: (2020)

Therapeutic Potential and Immunomodulatory Role of Coenzyme Q(10) and Its Analogues in Systemic Autoimmune Diseases
por: López-Pedrera, Chary, et al.
Publicado: (2021)

Subclinical cardiovascular risk signs in adults with juvenile idiopathic arthritis in sustained remission
por: Aranda-Valera, Inmaculada Concepción, et al.
Publicado: (2020)

‘Atherothrombosis-associated microRNAs in Antiphospholipid syndrome and Systemic Lupus Erythematosus patients’
por: Pérez-Sánchez, C., et al.
Publicado: (2016)

Myocardial infarction in an 11-year-old child with systemic lupus erythematosus
por: Bilici, Meki, et al.
Publicado: (2016)

Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility
por: Baskin, Rebekah, et al.
Publicado: (2015)

Integrative Bioinformatics Analysis Identifies DDX60 as a Potential Biomarker for Systemic Lupus Erythematosus
por: Chen, Wu, et al.
Publicado: (2023)

Impaired microRNA processing in neutrophils from rheumatoid arthritis patients confers their pathogenic profile. Modulation by biological therapies
por: de la Rosa, Ivan Arias, et al.
Publicado: (2020)

Complement component 3 as biomarker of disease activity and cardiometabolic risk factor in rheumatoid arthritis and spondyloarthritis
por: Arias de la Rosa, Iván, et al.
Publicado: (2020)

Molecular Characterization of Monocyte Subsets Reveals Specific and Distinctive Molecular Signatures Associated With Cardiovascular Disease in Rheumatoid Arthritis
por: Ruiz-Limon, Patricia, et al.
Publicado: (2019)

Splicing machinery is impaired in rheumatoid arthritis, associated with disease activity and modulated by anti-TNF therapy
por: Ibáñez-Costa, Alejandro, et al.
Publicado: (2022)

DDX11-AS1 as potential therapy targets for human hepatocellular carcinoma
por: Shi, Min, et al.
Publicado: (2017)

Role of the DDX11 DNA Helicase in Warsaw Breakage Syndrome Etiology
por: Santos, Diana, et al.
Publicado: (2021)

Therapeutic Plasma Exchange as Management of Complicated Systemic Lupus Erythematosus and Other Autoimmune Diseases
por: Aguirre-Valencia, David, et al.
Publicado: (2019)

Dnm1’s recruitment strategy
por: Short, Ben
Publicado: (2012)

The DEAD/DEAH box helicase, DDX11, is essential for the survival of advanced melanomas
por: Bhattacharya, Chitralekha, et al.
Publicado: (2012)

Molecular and Cellular Functions of the Warsaw Breakage Syndrome DNA Helicase DDX11
por: Pisani, Francesca M., et al.
Publicado: (2018)

The Genome Stability Maintenance DNA Helicase DDX11 and Its Role in Cancer
por: Mahtab, Mohammad, et al.
Publicado: (2021)

DDX11L: a novel transcript family emerging from human subtelomeric regions
por: Costa, Valerio, et al.
Publicado: (2009)

Molecular Changes in the Adipose Tissue Induced by Rheumatoid Arthritis: Effects of Disease-Modifying Anti-Rheumatic Drugs
por: Arias de la Rosa, Iván, et al.
Publicado: (2021)

The Role of Upregulated DDX11 as A Potential Prognostic and Diagnostic Biomarker in Lung Adenocarcinoma
por: Li, Jianhao, et al.
Publicado: (2019)

DDX11 loss causes replication stress and pharmacologically exploitable DNA repair defects
por: Jegadesan, Nanda Kumar, et al.
Publicado: (2021)

The clinical and molecular cardiometabolic fingerprint of an exploratory psoriatic arthritis cohort is associated with the disease activity and differentially modulated by methotrexate and apremilast
por: Arias de la Rosa, Ivan, et al.
Publicado: (2022)

Association of the CD11b rs1143679 polymorphism with systemic lupus erythematosus in the Han Chinese population
por: Li, Chunmei, et al.
Publicado: (2017)

Predictors of major infections in systemic lupus erythematosus
por: Ruiz-Irastorza, Guillermo, et al.
Publicado: (2009)

Polymorphisms in the Hsp70 gene locus are genetically associated with systemic lupus erythematosus
por: Fürnrohr, Barbara G, et al.
Publicado: (2010)

Classical dynamin DNM1 and DNM3 genes attain maximum expression in the normal human central nervous system
por: Romeu, Antoni, et al.
Publicado: (2014)

Timeless couples G‐quadruplex detection with processing by DDX11 helicase during DNA replication
por: Lerner, Leticia K, et al.
Publicado: (2020)

Nonalcoholic fatty liver disease in inflammatory arthritis: Relationship with cardiovascular risk
por: Barbarroja, Nuria, et al.
Publicado: (2022)

Discovery of a novel genetic susceptibility locus on X chromosome for systemic lupus erythematosus
por: Zhu, Zhengwei, et al.
Publicado: (2015)

The iron–sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation
por: Simon, Anna K, et al.
Publicado: (2020)

DNA Nanomachine (DNM) Biplex Assay for Differentiating Bacillus cereus Species
por: Ateiah, Muhannad, et al.
Publicado: (2023)

Lupus Erythematosus
por: Gardiner, Frederick
Publicado: (1923)

Lupus Erythematosus
por: Ravogli, A.
Publicado: (1887)

Phenotypic Spectrum of DNM2-Related Centronuclear Myopathy
por: Hayes, Leslie Hotchkiss, et al.
Publicado: (2022)

Deletion at an 1q24 locus reveals a critical role of long noncoding RNA DNM3OS in skeletal development
por: Yu, Ting-ting, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l2delfnka1vhefqvshjj761ecg