Cargando…
Phosphorylation of mRNA-Binding Proteins Puf1 and Puf2 by TORC2-Activated Protein Kinase Ypk1 Alleviates Their Repressive Effects
Members of the Puf family of RNA-binding proteins typically associate via their Pumilio homology domain with specific short motifs in the 3’-UTR of an mRNA and thereby influence the stability, localization and/or efficiency of translation of the bound transcript. In our prior unbiased proteome-wide...
Autores principales: | Galez, Henri A., Roelants, Françoise M., Palm, Sarah M., Reynaud, Kendra K., Ingolia, Nicholas T., Thorner, Jeremy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304900/ https://www.ncbi.nlm.nih.gov/pubmed/34209236 http://dx.doi.org/10.3390/membranes11070500 |
Ejemplares similares
-
TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids
por: Muir, Alexander, et al.
Publicado: (2014) -
The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites
por: Leskoske, Kristin L., et al.
Publicado: (2017) -
Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress
por: Muir, Alexander, et al.
Publicado: (2015) -
TORC2-Dependent Ypk1-Mediated Phosphorylation of Lam2/Ltc4 Disrupts Its Association with the β-Propeller Protein Laf1 at Endoplasmic Reticulum-Plasma Membrane Contact Sites in the Yeast Saccharomyces cerevisiae
por: Topolska, Magdalena, et al.
Publicado: (2020) -
Identification and characterization of roles for Puf1 and Puf2 proteins in the yeast response to high calcium
por: Haramati, Ofir, et al.
Publicado: (2017)