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Pilot Study of Acupuncture’s Antispasmodic Effect on Upper Gastrointestinal Tract during Endoscopic Submucosal Dissection for Early Gastric Cancer: Controlled Clinical Trial

A prospective study was conducted in patients with early-stage gastric cancer to determine the efficacy and safety of acupuncture stimulation as an antispasmodic compared with conventional medication during the procedure of endoscopic submucosal dissection (ESD) of the upper gastrointestinal tract....

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Autores principales: Suzuki, Masao, Ishizaki, Naoto, Kayo, Takumi, Furuta, Taiga, Igarashi, Ryo, Maki, Takumi, Hoshi, Koki, Yamabe, Akane, Fujisawa, Mariko, Funakubo, Akira, Mitsuma, Tadamichi, Irisawa, Atsushi, Shibukawa, Goro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305036/
https://www.ncbi.nlm.nih.gov/pubmed/34300215
http://dx.doi.org/10.3390/jcm10143050
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author Suzuki, Masao
Ishizaki, Naoto
Kayo, Takumi
Furuta, Taiga
Igarashi, Ryo
Maki, Takumi
Hoshi, Koki
Yamabe, Akane
Fujisawa, Mariko
Funakubo, Akira
Mitsuma, Tadamichi
Irisawa, Atsushi
Shibukawa, Goro
author_facet Suzuki, Masao
Ishizaki, Naoto
Kayo, Takumi
Furuta, Taiga
Igarashi, Ryo
Maki, Takumi
Hoshi, Koki
Yamabe, Akane
Fujisawa, Mariko
Funakubo, Akira
Mitsuma, Tadamichi
Irisawa, Atsushi
Shibukawa, Goro
author_sort Suzuki, Masao
collection PubMed
description A prospective study was conducted in patients with early-stage gastric cancer to determine the efficacy and safety of acupuncture stimulation as an antispasmodic compared with conventional medication during the procedure of endoscopic submucosal dissection (ESD) of the upper gastrointestinal tract. This study was a prospective single blinded quasi-randomized controlled trial. Seventy-three patients who were scheduled to undergo ESD for gastric cancer at Aizu Medical Center between 19 February 2016 and 30 June 2016 were assessed for eligibility for the study. Sixty out of 73 patients were included in the study and assigned into two intervention groups: medication group (MG) and acupuncture group (AG). Ease of the procedure was evaluated using modified NIWA classification (MNC) by endoscopist considering the frequency and amplitude of the upper gastrointestinal peristalsis. For the statistical analysis, Mann–Whitney test was used to compare the differences of MNC values (baseline and end of procedure) between two groups. The difference of MNC found in the AG (−2.00 (−3.0 to −2.0)) was significantly greater than that in the MG (−1.00 (−2.0 to −1.0), p < 0.0001, Mann–Whitney test). We consider that acupuncture to the abdomen could be an alternative antispasmodic method during upper gastrointestinal endoscopic procedure.
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spelling pubmed-83050362021-07-25 Pilot Study of Acupuncture’s Antispasmodic Effect on Upper Gastrointestinal Tract during Endoscopic Submucosal Dissection for Early Gastric Cancer: Controlled Clinical Trial Suzuki, Masao Ishizaki, Naoto Kayo, Takumi Furuta, Taiga Igarashi, Ryo Maki, Takumi Hoshi, Koki Yamabe, Akane Fujisawa, Mariko Funakubo, Akira Mitsuma, Tadamichi Irisawa, Atsushi Shibukawa, Goro J Clin Med Article A prospective study was conducted in patients with early-stage gastric cancer to determine the efficacy and safety of acupuncture stimulation as an antispasmodic compared with conventional medication during the procedure of endoscopic submucosal dissection (ESD) of the upper gastrointestinal tract. This study was a prospective single blinded quasi-randomized controlled trial. Seventy-three patients who were scheduled to undergo ESD for gastric cancer at Aizu Medical Center between 19 February 2016 and 30 June 2016 were assessed for eligibility for the study. Sixty out of 73 patients were included in the study and assigned into two intervention groups: medication group (MG) and acupuncture group (AG). Ease of the procedure was evaluated using modified NIWA classification (MNC) by endoscopist considering the frequency and amplitude of the upper gastrointestinal peristalsis. For the statistical analysis, Mann–Whitney test was used to compare the differences of MNC values (baseline and end of procedure) between two groups. The difference of MNC found in the AG (−2.00 (−3.0 to −2.0)) was significantly greater than that in the MG (−1.00 (−2.0 to −1.0), p < 0.0001, Mann–Whitney test). We consider that acupuncture to the abdomen could be an alternative antispasmodic method during upper gastrointestinal endoscopic procedure. MDPI 2021-07-09 /pmc/articles/PMC8305036/ /pubmed/34300215 http://dx.doi.org/10.3390/jcm10143050 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Suzuki, Masao
Ishizaki, Naoto
Kayo, Takumi
Furuta, Taiga
Igarashi, Ryo
Maki, Takumi
Hoshi, Koki
Yamabe, Akane
Fujisawa, Mariko
Funakubo, Akira
Mitsuma, Tadamichi
Irisawa, Atsushi
Shibukawa, Goro
Pilot Study of Acupuncture’s Antispasmodic Effect on Upper Gastrointestinal Tract during Endoscopic Submucosal Dissection for Early Gastric Cancer: Controlled Clinical Trial
title Pilot Study of Acupuncture’s Antispasmodic Effect on Upper Gastrointestinal Tract during Endoscopic Submucosal Dissection for Early Gastric Cancer: Controlled Clinical Trial
title_full Pilot Study of Acupuncture’s Antispasmodic Effect on Upper Gastrointestinal Tract during Endoscopic Submucosal Dissection for Early Gastric Cancer: Controlled Clinical Trial
title_fullStr Pilot Study of Acupuncture’s Antispasmodic Effect on Upper Gastrointestinal Tract during Endoscopic Submucosal Dissection for Early Gastric Cancer: Controlled Clinical Trial
title_full_unstemmed Pilot Study of Acupuncture’s Antispasmodic Effect on Upper Gastrointestinal Tract during Endoscopic Submucosal Dissection for Early Gastric Cancer: Controlled Clinical Trial
title_short Pilot Study of Acupuncture’s Antispasmodic Effect on Upper Gastrointestinal Tract during Endoscopic Submucosal Dissection for Early Gastric Cancer: Controlled Clinical Trial
title_sort pilot study of acupuncture’s antispasmodic effect on upper gastrointestinal tract during endoscopic submucosal dissection for early gastric cancer: controlled clinical trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305036/
https://www.ncbi.nlm.nih.gov/pubmed/34300215
http://dx.doi.org/10.3390/jcm10143050
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