Systemic T Cell Exhaustion Dynamics Is Linked to Early High Mobility Group Box Protein 1 (HMGB1) Driven Hyper-Inflammation in a Polytrauma Rat Model

We previously reported an early surge in high mobility group box protein 1 (HMGB1) levels in a polytrauma (PT) rat model. This study investigates the association of HMGB1 levels in mediating PT associated dysregulated immune responses and its influence on the cellular levels of receptor for advanced...

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Detalles Bibliográficos
Autores principales: Muire, Preeti J., Schwacha, Martin G., Wenke, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305113/
https://www.ncbi.nlm.nih.gov/pubmed/34209240
http://dx.doi.org/10.3390/cells10071646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305113/
https://www.ncbi.nlm.nih.gov/pubmed/34209240
http://dx.doi.org/10.3390/cells10071646

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