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A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability

Resveratrol (RES) has a low bioavailability. This limitation was addressed in an earlier review and several recommendations were offered. A literature search was conducted in order to determine the extent of the research that was conducted in line with these recommendations, along with new developme...

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Detalles Bibliográficos
Autores principales: de Vries, Konrad, Strydom, Morné, Steenkamp, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305180/
https://www.ncbi.nlm.nih.gov/pubmed/34299642
http://dx.doi.org/10.3390/molecules26144367
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author de Vries, Konrad
Strydom, Morné
Steenkamp, Vanessa
author_facet de Vries, Konrad
Strydom, Morné
Steenkamp, Vanessa
author_sort de Vries, Konrad
collection PubMed
description Resveratrol (RES) has a low bioavailability. This limitation was addressed in an earlier review and several recommendations were offered. A literature search was conducted in order to determine the extent of the research that was conducted in line with these recommendations, along with new developments in this field. Most of the identified studies were pre-clinical and confirmed the heightened activity of RES analogues compared to their parent compound. Although this has provided additional scientific kudos for these compounds and has strengthened their potential to be developed into phytopharmaceutical products, clinical trials designed to confirm this increased activity remain lacking and are warranted.
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spelling pubmed-83051802021-07-25 A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability de Vries, Konrad Strydom, Morné Steenkamp, Vanessa Molecules Review Resveratrol (RES) has a low bioavailability. This limitation was addressed in an earlier review and several recommendations were offered. A literature search was conducted in order to determine the extent of the research that was conducted in line with these recommendations, along with new developments in this field. Most of the identified studies were pre-clinical and confirmed the heightened activity of RES analogues compared to their parent compound. Although this has provided additional scientific kudos for these compounds and has strengthened their potential to be developed into phytopharmaceutical products, clinical trials designed to confirm this increased activity remain lacking and are warranted. MDPI 2021-07-20 /pmc/articles/PMC8305180/ /pubmed/34299642 http://dx.doi.org/10.3390/molecules26144367 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
de Vries, Konrad
Strydom, Morné
Steenkamp, Vanessa
A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability
title A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability
title_full A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability
title_fullStr A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability
title_full_unstemmed A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability
title_short A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability
title_sort brief updated review of advances to enhance resveratrol’s bioavailability
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305180/
https://www.ncbi.nlm.nih.gov/pubmed/34299642
http://dx.doi.org/10.3390/molecules26144367
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