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Combinatorial Virtual Library Screening Study of Transforming Growth Factor-β2–Chondroitin Sulfate System

Transforming growth factor-beta (TGF-β), a member of the TGF-β cytokine superfamily, is known to bind to sulfated glycosaminoglycans (GAGs), but the nature of this interaction remains unclear. In a recent study, we found that preterm human milk TGF-β2 is sequestered by chondroitin sulfate (CS) in it...

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Detalles Bibliográficos
Autores principales: Sankaranarayanan, Nehru Viji, Nagarajan, Balaji, Desai, Umesh R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305211/
https://www.ncbi.nlm.nih.gov/pubmed/34299163
http://dx.doi.org/10.3390/ijms22147542