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The Level of Conus Medullaris in 629 Healthy Japanese Individuals
The conus medullaris typically terminates at the L1 level; however, variations in its level and the factors associated with the conus medullaris level are unclear. We investigated the level of conus medullaris on magnetic resonance imaging in healthy volunteers. In total, 629 healthy adult volunteer...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305241/ https://www.ncbi.nlm.nih.gov/pubmed/34300348 http://dx.doi.org/10.3390/jcm10143182 |
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author | Nakashima, Hiroaki Ito, Keigo Katayama, Yoshito Tsushima, Mikito Ando, Kei Kobayashi, Kazuyoshi Machino, Masaaki Ito, Sadayuki Koshimizu, Hiroyuki Segi, Naoki Tomita, Hiroyuki Imagama, Shiro |
author_facet | Nakashima, Hiroaki Ito, Keigo Katayama, Yoshito Tsushima, Mikito Ando, Kei Kobayashi, Kazuyoshi Machino, Masaaki Ito, Sadayuki Koshimizu, Hiroyuki Segi, Naoki Tomita, Hiroyuki Imagama, Shiro |
author_sort | Nakashima, Hiroaki |
collection | PubMed |
description | The conus medullaris typically terminates at the L1 level; however, variations in its level and the factors associated with the conus medullaris level are unclear. We investigated the level of conus medullaris on magnetic resonance imaging in healthy volunteers. In total, 629 healthy adult volunteers (≥50 individuals of each sex and in each decade of age from 20 to 70) were enrolled. The level of the conus medullaris was assessed based on the T2-weighted sagittal magnetic resonance images, and factors affecting its level were investigated employing multivariate regression analysis including the participants’ background and radiographical parameters. L1 was the most common conus medullaris level. Participant height was significantly shorter in the caudally placed conus medullaris (p = 0.013). With respect to the radiographical parameters, pelvic incidence (p = 0.003), and pelvic tilt (p = 0.03) were significantly smaller in participants with a caudally placed conus medullaris. Multiple regression analysis showed that the pelvic incidence (p < 0.0001) and height (p < 0.0001) were significant factors affecting the conus medullaris level. These results indicated that the length of the spinal cord varies little among individuals and that skeletal differences affect the level of the conus medullaris. |
format | Online Article Text |
id | pubmed-8305241 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83052412021-07-25 The Level of Conus Medullaris in 629 Healthy Japanese Individuals Nakashima, Hiroaki Ito, Keigo Katayama, Yoshito Tsushima, Mikito Ando, Kei Kobayashi, Kazuyoshi Machino, Masaaki Ito, Sadayuki Koshimizu, Hiroyuki Segi, Naoki Tomita, Hiroyuki Imagama, Shiro J Clin Med Article The conus medullaris typically terminates at the L1 level; however, variations in its level and the factors associated with the conus medullaris level are unclear. We investigated the level of conus medullaris on magnetic resonance imaging in healthy volunteers. In total, 629 healthy adult volunteers (≥50 individuals of each sex and in each decade of age from 20 to 70) were enrolled. The level of the conus medullaris was assessed based on the T2-weighted sagittal magnetic resonance images, and factors affecting its level were investigated employing multivariate regression analysis including the participants’ background and radiographical parameters. L1 was the most common conus medullaris level. Participant height was significantly shorter in the caudally placed conus medullaris (p = 0.013). With respect to the radiographical parameters, pelvic incidence (p = 0.003), and pelvic tilt (p = 0.03) were significantly smaller in participants with a caudally placed conus medullaris. Multiple regression analysis showed that the pelvic incidence (p < 0.0001) and height (p < 0.0001) were significant factors affecting the conus medullaris level. These results indicated that the length of the spinal cord varies little among individuals and that skeletal differences affect the level of the conus medullaris. MDPI 2021-07-19 /pmc/articles/PMC8305241/ /pubmed/34300348 http://dx.doi.org/10.3390/jcm10143182 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Nakashima, Hiroaki Ito, Keigo Katayama, Yoshito Tsushima, Mikito Ando, Kei Kobayashi, Kazuyoshi Machino, Masaaki Ito, Sadayuki Koshimizu, Hiroyuki Segi, Naoki Tomita, Hiroyuki Imagama, Shiro The Level of Conus Medullaris in 629 Healthy Japanese Individuals |
title | The Level of Conus Medullaris in 629 Healthy Japanese Individuals |
title_full | The Level of Conus Medullaris in 629 Healthy Japanese Individuals |
title_fullStr | The Level of Conus Medullaris in 629 Healthy Japanese Individuals |
title_full_unstemmed | The Level of Conus Medullaris in 629 Healthy Japanese Individuals |
title_short | The Level of Conus Medullaris in 629 Healthy Japanese Individuals |
title_sort | level of conus medullaris in 629 healthy japanese individuals |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305241/ https://www.ncbi.nlm.nih.gov/pubmed/34300348 http://dx.doi.org/10.3390/jcm10143182 |
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