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The Level of Conus Medullaris in 629 Healthy Japanese Individuals

The conus medullaris typically terminates at the L1 level; however, variations in its level and the factors associated with the conus medullaris level are unclear. We investigated the level of conus medullaris on magnetic resonance imaging in healthy volunteers. In total, 629 healthy adult volunteer...

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Autores principales: Nakashima, Hiroaki, Ito, Keigo, Katayama, Yoshito, Tsushima, Mikito, Ando, Kei, Kobayashi, Kazuyoshi, Machino, Masaaki, Ito, Sadayuki, Koshimizu, Hiroyuki, Segi, Naoki, Tomita, Hiroyuki, Imagama, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305241/
https://www.ncbi.nlm.nih.gov/pubmed/34300348
http://dx.doi.org/10.3390/jcm10143182
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author Nakashima, Hiroaki
Ito, Keigo
Katayama, Yoshito
Tsushima, Mikito
Ando, Kei
Kobayashi, Kazuyoshi
Machino, Masaaki
Ito, Sadayuki
Koshimizu, Hiroyuki
Segi, Naoki
Tomita, Hiroyuki
Imagama, Shiro
author_facet Nakashima, Hiroaki
Ito, Keigo
Katayama, Yoshito
Tsushima, Mikito
Ando, Kei
Kobayashi, Kazuyoshi
Machino, Masaaki
Ito, Sadayuki
Koshimizu, Hiroyuki
Segi, Naoki
Tomita, Hiroyuki
Imagama, Shiro
author_sort Nakashima, Hiroaki
collection PubMed
description The conus medullaris typically terminates at the L1 level; however, variations in its level and the factors associated with the conus medullaris level are unclear. We investigated the level of conus medullaris on magnetic resonance imaging in healthy volunteers. In total, 629 healthy adult volunteers (≥50 individuals of each sex and in each decade of age from 20 to 70) were enrolled. The level of the conus medullaris was assessed based on the T2-weighted sagittal magnetic resonance images, and factors affecting its level were investigated employing multivariate regression analysis including the participants’ background and radiographical parameters. L1 was the most common conus medullaris level. Participant height was significantly shorter in the caudally placed conus medullaris (p = 0.013). With respect to the radiographical parameters, pelvic incidence (p = 0.003), and pelvic tilt (p = 0.03) were significantly smaller in participants with a caudally placed conus medullaris. Multiple regression analysis showed that the pelvic incidence (p < 0.0001) and height (p < 0.0001) were significant factors affecting the conus medullaris level. These results indicated that the length of the spinal cord varies little among individuals and that skeletal differences affect the level of the conus medullaris.
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spelling pubmed-83052412021-07-25 The Level of Conus Medullaris in 629 Healthy Japanese Individuals Nakashima, Hiroaki Ito, Keigo Katayama, Yoshito Tsushima, Mikito Ando, Kei Kobayashi, Kazuyoshi Machino, Masaaki Ito, Sadayuki Koshimizu, Hiroyuki Segi, Naoki Tomita, Hiroyuki Imagama, Shiro J Clin Med Article The conus medullaris typically terminates at the L1 level; however, variations in its level and the factors associated with the conus medullaris level are unclear. We investigated the level of conus medullaris on magnetic resonance imaging in healthy volunteers. In total, 629 healthy adult volunteers (≥50 individuals of each sex and in each decade of age from 20 to 70) were enrolled. The level of the conus medullaris was assessed based on the T2-weighted sagittal magnetic resonance images, and factors affecting its level were investigated employing multivariate regression analysis including the participants’ background and radiographical parameters. L1 was the most common conus medullaris level. Participant height was significantly shorter in the caudally placed conus medullaris (p = 0.013). With respect to the radiographical parameters, pelvic incidence (p = 0.003), and pelvic tilt (p = 0.03) were significantly smaller in participants with a caudally placed conus medullaris. Multiple regression analysis showed that the pelvic incidence (p < 0.0001) and height (p < 0.0001) were significant factors affecting the conus medullaris level. These results indicated that the length of the spinal cord varies little among individuals and that skeletal differences affect the level of the conus medullaris. MDPI 2021-07-19 /pmc/articles/PMC8305241/ /pubmed/34300348 http://dx.doi.org/10.3390/jcm10143182 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nakashima, Hiroaki
Ito, Keigo
Katayama, Yoshito
Tsushima, Mikito
Ando, Kei
Kobayashi, Kazuyoshi
Machino, Masaaki
Ito, Sadayuki
Koshimizu, Hiroyuki
Segi, Naoki
Tomita, Hiroyuki
Imagama, Shiro
The Level of Conus Medullaris in 629 Healthy Japanese Individuals
title The Level of Conus Medullaris in 629 Healthy Japanese Individuals
title_full The Level of Conus Medullaris in 629 Healthy Japanese Individuals
title_fullStr The Level of Conus Medullaris in 629 Healthy Japanese Individuals
title_full_unstemmed The Level of Conus Medullaris in 629 Healthy Japanese Individuals
title_short The Level of Conus Medullaris in 629 Healthy Japanese Individuals
title_sort level of conus medullaris in 629 healthy japanese individuals
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305241/
https://www.ncbi.nlm.nih.gov/pubmed/34300348
http://dx.doi.org/10.3390/jcm10143182
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